2026 ICD-10-CM Diagnosis Code A48.3Toxic shock syndrome

ICD-10-CM Codes›A00–B99›A30-A49›A48

ICD-10-CM A48.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

A48.3 is a billable ICD-10-CM diagnosis code for toxic shock syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 867 through 869. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Bacterial infections.

Code Identity

ICD-10-CM Code
A48.3
Billable Status
Yes — Valid for Submission
Code Describes
Toxic shock syndrome
Short Description
Toxic shock syndrome
Same as the full description in the CMS dataset.
Parent Code
A48
Other bacterial diseases, not elsewhere classified

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA30-A49Other bacterial diseases
CategoryA48Other bacterial diseases, not elsewhere classified
This CodeA48.3Toxic shock syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Infection by methicillin sensitive Staphylococcus aureus
  • Methicillin resistant Staphylococcus aureus infection
  • Staphylococcal toxic shock syndrome
  • Streptococcal toxic shock syndrome
  • Streptococcus pyogenes infection
  • Toxic shock syndrome
  • Toxic shock syndrome caused by methicillin resistant Staphylococcus aureus infection
  • Toxic shock syndrome caused by methicillin susceptible Staphylococcus aureus

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Use Additional Code

  • code to identify the organism B95 B96

Type 1 Excludes

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Shock
      • toxic, syndrome
    • Syndrome
      • shock (traumatic)
        • toxic
    • Syndrome
      • toxic shock
    • Toxic(poisoning)
      • shock syndrome

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF003
Bacterial infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Sepsis

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

The full article covers:

  • What is sepsis?
  • What causes sepsis?
  • Who is more likely to develop sepsis?
  • What are the symptoms of sepsis?
  • What other problems can sepsis cause?
  • How is sepsis diagnosed?
  • What are the treatments for sepsis?
  • Can sepsis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A48.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
040.82 Toxic shock syndrome
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About A48.3Overview

Is A48.3 (Other bacterial diseases, not elsewhere classified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic shock syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does A48.3 group to?

When toxic shock syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 868, 869, with relative weights from 0.7297 to 2.0932 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of A48.3?

Under the General Equivalence Mappings, toxic shock syndrome converts to ICD-9-CM 040.82 (toxic shock syndrome). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.