2027 ICD-10-CM Diagnosis Code A06.6Amebic brain abscess
ICD-10-CM Codes›A00–B99›A00-A09›A06
- Billable — Valid for Submission
- MCC — Major Complication or Comorbidity
- Not Chronic
A06.6 is a billable ICD-10-CM diagnosis code for amebic brain abscess. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 23 through 24, 97 through 99. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 2 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under CNS abscess; and Parasitic, other specified and unspecified infections.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Amebic brain abscess
- Amebic infection of central nervous system
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to A06.6: its own notes plus those printed at A06 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- infection due to Entamoeba histolytica
- diseases generally recognized as communicable or transmissible
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Amebic abscess of brain (and liver) (and lung)
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify resistance to antimicrobial drugs (Z16.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name A06.6, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming A06.6: they are not reported together with it, unless the two conditions are unrelated.
- G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhereamebic (A06.6)
- Block B50-B64 Protozoal diseasesamebiasis (A06.-) names A06.-, which includes this code
Excludes2 2
These codes carry an Excludes2 note naming A06.6: its condition is not part of those codes, and both may be reported when the patient has both.
- Block P35-P39 Infections specific to the perinatal period
- P37 Other congenital infectious and parasitic diseases
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Amebiasis
infection with any of various amebae. it is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.
Patient EducationClinical
Abscess
An abscess is a pocket of pus. You can get an abscess almost anywhere in your body. When an area of your body becomes infected, your body's immune system tries to fight the infection. White blood cells go to the infected area, collect within the damaged tissue, and cause inflammation. During this process, pus forms.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert A06.6 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About A06.6Overview
What is the ICD-10 code for amebic brain abscess?
The ICD-10-CM code for amebic brain abscess is A06.6 (sometimes written as A066). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is A06.6 (Amebiasis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report amebic brain abscess on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does A06.6 group to?
When amebic brain abscess is the principal diagnosis on an inpatient stay, it groups to MS-DRG 24, 98, 99, 23, 97, with relative weights from 1.5249 to 5.7422 depending on complications. Higher weights mean higher Medicare reimbursement.
Is A06.6 a CC or MCC?
CMS lists A06.6 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 2 closely related codes in its exclusion list.
Can A06.6 be reported with a code from A07?
Not as a rule. The Excludes1 note at A06, which applies to A06.6, lists "other protozoal intestinal diseases (A07.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
