2026 ICD-10-CM Diagnosis Code A06.6Amebic brain abscess

ICD-10-CM Codes›A00–B99›A00-A09›A06

ICD-10-CM A06.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

A06.6 is a billable ICD-10-CM diagnosis code for amebic brain abscess. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under CNS abscess; and Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
A06.6
Billable Status
Yes — Valid for Submission
Code Describes
Amebic brain abscess
Short Description
Amebic brain abscess
Same as the full description in the CMS dataset.
Parent Code
A06
Amebiasis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA00-A09Intestinal infectious diseases
CategoryA06Amebiasis
This CodeA06.6Amebic brain abscess

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Amebic brain abscess
  • Amebic infection of central nervous system

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Amebic abscess of brain (and liver) (and lung)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abscess(connective tissue) (embolic) (fistulous) (infective) (metastatic) (multiple) (pernicious) (pyogenic) (septic)
      • amebic
        • brain (and liver or lung abscess)
    • Abscess(connective tissue) (embolic) (fistulous) (infective) (metastatic) (multiple) (pernicious) (pyogenic) (septic)
      • brain (any part) (cystic) (otogenic)
        • amebic (with abscess of any other site)
    • Abscess(connective tissue) (embolic) (fistulous) (infective) (metastatic) (multiple) (pernicious) (pyogenic) (septic)
      • liver (cholangitic) (hematogenic) (lymphogenic) (pylephlebitic) (pyogenic)
        • amebic (due to Entamoeba histolytica) (dysenteric) (tropical)
          • with
            • brain abscess (and liver or lung abscess)
    • Abscess(connective tissue) (embolic) (fistulous) (infective) (metastatic) (multiple) (pernicious) (pyogenic) (septic)
      • lung (miliary) (putrid)
        • amebic (with liver abscess)
          • with
            • brain abscess

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS014
CNS abscess
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Amebiasis

    infection with any of various amebae. it is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.

  • Dysentery, Amebic

    dysentery caused by intestinal amebic infection, chiefly with entamoeba histolytica. this condition may be associated with amebic infection of the liver and other distant sites.

  • Liver Abscess, Amebic

    single or multiple areas of pus due to infection by any ameboid protozoa (amebiasis). a common form is caused by the ingestion of entamoeba histolytica.

  • Amebiasis|Amoebiasis|Amoebiasis

    a parasitic infection of the colon by entamoeba histolytica. signs and symptoms include cramping, diarrhea, bloody stools and fever. it can be treated with antibiotics.

  • Amebiasis

    a parasitic infectious disorder caused by amoebas. the parasite may cause colitis which is manifested with bloody diarrhea, abdominal pain, nausea and fever. in rare cases it may spread to the liver, brain and lungs.

Patient EducationClinical

Abscess

An abscess is a pocket of pus. You can get an abscess almost anywhere in your body. When an area of your body becomes infected, your body's immune system tries to fight the infection. White blood cells go to the infected area, collect within the damaged tissue, and cause inflammation. During this process, pus forms.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A06.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
006.5 Amebic brain abscess
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About A06.6Overview

Is A06.6 (Amebiasis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report amebic brain abscess on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of A06.6?

Under the General Equivalence Mappings, amebic brain abscess converts to ICD-9-CM 006.5 (amebic brain abscess). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.