ICD-10 Diagnosis Code D68.52

Prothrombin gene mutation

Diagnosis Code D68.52

ICD-10: D68.52
Short Description: Prothrombin gene mutation
Long Description: Prothrombin gene mutation
This is the 2017 version of the ICD-10-CM diagnosis code D68.52

Code Classification
  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    • Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
      • Other coagulation defects (D68)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code D68.52 is grouped in the following Diagnostic Related Group(s) (MS-DRG v33.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Heterozygous prothrombin G20210A mutation
  • Homozygous prothrombin G20210A mutation
  • Prothrombin G20210A mutation

Information for Patients

Bleeding Disorders

Also called: Clotting disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Bleeding disorders can be the result of other diseases, such as severe liver disease. They can also be inherited. Hemophilia is an inherited bleeding disorder. Bleeding disorders can also be a side effect of medicines.

  • Bleeding disorders
  • Bleeding time
  • Disseminated intravascular coagulation (DIC)
  • Partial thromboplastin time (PTT)
  • Prothrombin time (PT)

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Prothrombin thrombophilia Prothrombin thrombophilia is an inherited disorder of blood clotting. Thrombophilia is an increased tendency to form abnormal blood clots in blood vessels. People who have prothrombin thrombophilia are at somewhat higher than average risk for a type of clot called a deep venous thrombosis, which typically occurs in the deep veins of the legs. Affected people also have an increased risk of developing a pulmonary embolism, which is a clot that travels through the bloodstream and lodges in the lungs. Most people with prothrombin thrombophilia never develop abnormal blood clots, however.Some research suggests that prothrombin thrombophilia is associated with a somewhat increased risk of pregnancy loss (miscarriage) and may also increase the risk of other complications during pregnancy. These complications may include pregnancy-induced high blood pressure (preeclampsia), slow fetal growth, and early separation of the placenta from the uterine wall (placental abruption). It is important to note, however, that most women with prothrombin thrombophilia have normal pregnancies.
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