Hypercoagulable (state)

Alphabetical Index

Use the alphabetical index for the main term hypercoagulable (state) to review the available sub terms and properly select the ICD-10 code with the highest degree of specificity. Instructional notations will guide the coder with information such as "see", "see also", "with", "without", "due to", and "code by site".

  • Hypercoagulable (state) - D68.59 Other primary thrombophilia
    • activated protein C resistance - D68.51 Activated protein C resistance
    • antithrombin (III) deficiency - D68.59 Other primary thrombophilia
    • factor V Leiden mutation - D68.51 Activated protein C resistance
    • primary NEC - D68.59 Other primary thrombophilia
    • protein C deficiency - D68.59 Other primary thrombophilia
    • protein S deficiency - D68.59 Other primary thrombophilia
    • prothrombin gene mutation - D68.52 Prothrombin gene mutation
    • secondary - D68.69 Other thrombophilia
    • specified NEC - D68.69 Other thrombophilia

Clinical Terms

The following are some of the clinical term definitions related or applicable to hypercoagulable (state) within the ICD-10 index for Diseases and Injuries.

Protein S Deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)