ICD-10-CM Hypercoagulable (state) References

"Hypercoagulable (state)" Annotation Back-References in the ICD-10-CM Index to Diseases and Injuries

Browse the ICD-10-CM codes with references applicable to the clinical term "hypercoagulable (state)"

  • Hypercoagulable (state) - D68.59 Other primary thrombophilia
    • activated protein C resistance - D68.51 Activated protein C resistance
    • antithrombin (III) deficiency - D68.59 Other primary thrombophilia
    • factor V Leiden mutation - D68.51 Activated protein C resistance
    • primary NEC - D68.59 Other primary thrombophilia
    • protein C deficiency - D68.59 Other primary thrombophilia
    • protein S deficiency - D68.59 Other primary thrombophilia
    • prothrombin gene mutation - D68.52 Prothrombin gene mutation
    • secondary - D68.69 Other thrombophilia
    • specified NEC - D68.69 Other thrombophilia

Applicable Clinical Terms Definitions

Protein C Deficiency: An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)

Protein S Deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)