2026 ICD-10-CM Diagnosis Code Z22.7Latent tuberculosis

ICD-10-CM Codes›Z00–Z99›Z20-Z29›Z22

ICD-10-CM Z22.7
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z22.7 is a billable ICD-10-CM diagnosis code for latent tuberculosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as inactive tuberculosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Carrier status.

Code Identity

ICD-10-CM Code
Z22.7
Billable Status
Yes — Valid for Submission
Code Describes
Latent tuberculosis
Short Description
Latent tuberculosis
Same as the full description in the CMS dataset.
Parent Code
Z22
Carrier of infectious disease

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ20-Z29Persons with potential health hazards related to communicable diseases
CategoryZ22Carrier of infectious disease
This CodeZ22.7Latent tuberculosis

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z22.7.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z22.7 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Inactive tuberculosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Latent tuberculosis infection (LTBI)

Type 1 Excludes

  • nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis R76.12
  • nonspecific reaction to tuberculin skin test without active tuberculosis R76.11

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Infection, infected, infective(opportunistic)
      • tuberculous
        • latent (LTBI)
    • LTBI(latent tuberculosis infection)
    • Tuberculosis, tubercular, tuberculous(calcification) (calcified) (caseous) (chromogenic acid-fast bacilli) (degeneration) (fibrocaseous) (fistula) (interstitial) (isolated circumscribed lesions) (necrosis) (parenchymatous) (ulcerative)
      • abscess (respiratory)
        • latent
    • Tuberculosis, tubercular, tuberculous(calcification) (calcified) (caseous) (chromogenic acid-fast bacilli) (degeneration) (fibrocaseous) (fistula) (interstitial) (isolated circumscribed lesions) (necrosis) (parenchymatous) (ulcerative)
      • latent

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC024
Carrier status
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Latent Tuberculosis

    the dormant form of tuberculosis where the person shows no obvious symptoms and no sign of the causative agent (mycobacterium tuberculosis) in the sputum despite being positive for tuberculosis infection skin test.

Patient EducationClinical

Tuberculosis

Tuberculosis (TB) is a bacterial disease that usually attacks the lungs. But it can also attack other parts of the body, including the kidneys, spine, and brain.

The full article covers:

  • What is tuberculosis (TB)?
  • What causes tuberculosis (TB)?
  • Who is more likely to get infected with tuberculosis (TB) germs?
  • Who is more likely to develop TB disease?
  • What are the symptoms of tuberculosis (TB)?
  • How is tuberculosis (TB) diagnosed?
  • What is the treatment for tuberculosis (TB)?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement Z22.7 replaces the following previously assigned code(s):

  • R76.11 - Nonspecific reaction to skin test w/o active tuberculosis
FY 2020AddedAdded to the ICD-10-CM code setEffective October 1, 2019.
FY 2021–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z22.7Overview

Is Z22.7 (Carrier of infectious disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report latent tuberculosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z22.7 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because latent tuberculosis describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z22.7 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for latent tuberculosis on inpatient claims.