2026 ICD-10-CM Diagnosis Code Z22.358Carrier of other Enterobacterales

ICD-10-CM Codes›Z00–Z99›Z20-Z29›Z22

ICD-10-CM Z22.358
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z22.358 is a billable ICD-10-CM diagnosis code for carrier of other Enterobacterales. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as carrier of carbapenem sensitive Enterobacteriaceae. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Carrier status.

Code Identity

ICD-10-CM Code
Z22.358
Billable Status
Yes — Valid for Submission
Code Describes
Carrier of other Enterobacterales
Short Description
Carrier of other Enterobacterales
Same as the full description in the CMS dataset.
Parent Code
Z22.35
Carrier of Enterobacterales

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ20-Z29Persons with potential health hazards related to communicable diseases
CategoryZ22Carrier of infectious disease
This CodeZ22.358Carrier of other Enterobacterales

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z22.358.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z22.358 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Carrier of carbapenem sensitive Enterobacteriaceae

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Carrier of carbapenem-sensitive Enterobacterales
  • Carrier of ESBL-producing Enterobacterales
  • Carrier of extended-spectrum beta-lactamase producing Enterobacterales

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Carrier(suspected) of
      • Enterobacterales
        • carbapenem-sensitive
    • Carrier(suspected) of
      • Enterobacterales
        • Enterobacterales, specified type NEC
    • Carrier(suspected) of
      • Enterobacterales
        • ESBL-producing
    • Carrier(suspected) of
      • Enterobacterales
        • extended-spectrum beta-lactamase producing

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC024
Carrier status
Default principal diagnosis: inpatient No · outpatient Yes

Code History & ChangesHistory

Replacement Z22.358 replaces the following previously assigned code(s):

  • Z22.39 - Carrier of other specified bacterial diseases
FY 2024AddedAdded to the ICD-10-CM code setEffective October 1, 2023.
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z22.358Overview

Is Z22.358 (Carrier of Enterobacterales) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report carrier of other Enterobacterales on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z22.358 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because carrier of other Enterobacterales describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z22.358 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for carrier of other Enterobacterales on inpatient claims.