2026 ICD-10-CM Diagnosis Code Z22.350Carrier of carbapenem-resistant Enterobacterales

ICD-10-CM Codes›Z00–Z99›Z20-Z29›Z22

ICD-10-CM Z22.350
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z22.350 is a billable ICD-10-CM diagnosis code for carrier of carbapenem-resistant Enterobacterales. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Carrier status.

Code Identity

ICD-10-CM Code
Z22.350
Billable Status
Yes — Valid for Submission
Code Describes
Carrier of carbapenem-resistant Enterobacterales
Short Description
Carrier of carbapenem-resistant Enterobacterales
Same as the full description in the CMS dataset.
Parent Code
Z22.35
Carrier of Enterobacterales

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ20-Z29Persons with potential health hazards related to communicable diseases
CategoryZ22Carrier of infectious disease
This CodeZ22.350Carrier of carbapenem-resistant Enterobacterales

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z22.350.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z22.350 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Carrier(suspected) of
      • Enterobacterales
        • carbapenem-resistant

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC024
Carrier status
Default principal diagnosis: inpatient No · outpatient Yes

Code History & ChangesHistory

Replacement Z22.350 replaces the following previously assigned code(s):

  • Z22.39 - Carrier of other specified bacterial diseases
FY 2024AddedAdded to the ICD-10-CM code setEffective October 1, 2023.
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z22.350Overview

Is Z22.350 (Carrier of Enterobacterales) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report carrier of carbapenem-resistant Enterobacterales on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z22.350 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because carrier of carbapenem-resistant Enterobacterales describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z22.350 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for carrier of carbapenem-resistant Enterobacterales on inpatient claims.