2026 ICD-10-CM Diagnosis Code Z22.1Carrier of other intestinal infectious diseases

ICD-10-CM Codes›Z00–Z99›Z20-Z29›Z22

ICD-10-CM Z22.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z22.1 is a billable ICD-10-CM diagnosis code for carrier of other intestinal infectious diseases. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as asymptomatic carrier of infectious organism. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Carrier status.

Code Identity

ICD-10-CM Code
Z22.1
Billable Status
Yes — Valid for Submission
Code Describes
Carrier of other intestinal infectious diseases
Short Description
Carrier of other intestinal infectious diseases
Same as the full description in the CMS dataset.
Parent Code
Z22
Carrier of infectious disease

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ20-Z29Persons with potential health hazards related to communicable diseases
CategoryZ22Carrier of infectious disease
This CodeZ22.1Carrier of other intestinal infectious diseases

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z22.1.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z22.1 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Asymptomatic carrier of infectious organism
  • Asymptomatic enteric carriage of Entamoeba
  • Carrier of amebic protozoa
  • Carrier of Clostridioides difficile
  • Cholera carrier
  • Entamoeba carrier

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Carrier(suspected) of
      • amebiasis
    • Carrier(suspected) of
      • bacterial disease NEC
        • intestinal infectious NEC
    • Carrier(suspected) of
      • cholera
    • Carrier(suspected) of
      • gastrointestinal pathogens NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC024
Carrier status
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Gastroenteritis

Gastroenteritis is an inflammation of the lining of the stomach and intestines. The main symptoms include vomiting and diarrhea. It is usually not serious in healthy people, but it can sometimes lead to dehydration or cause severe symptoms.

The full article covers:

  • What is gastroenteritis?
  • What causes gastroenteritis?
  • What are the symptoms of gastroenteritis?
  • How is gastroenteritis diagnosed?
  • What are the treatments for gastroenteritis?
  • Can gastroenteritis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z22.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V02.0 Cholera carrier
Approximate The match is approximate rather than exact.
ICD-9-CM
V02.2 Amebiasis carrier
Approximate The match is approximate rather than exact.
ICD-9-CM
V02.3 GI pathogen carrier NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z22.1Overview

Is Z22.1 (Carrier of infectious disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report carrier of other intestinal infectious diseases on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z22.1 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because carrier of other intestinal infectious diseases describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z22.1 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for carrier of other intestinal infectious diseases on inpatient claims.

What is the ICD-9 equivalent of Z22.1?

Under the General Equivalence Mappings, carrier of other intestinal infectious diseases converts to ICD-9-CM V02.0 (cholera carrier), V02.2 (amebiasis carrier), and V02.3 (GI pathogen carrier NEC). The mapping is approximate, so confirm the match fits the documentation.