2026 ICD-10-CM Diagnosis Code R76.89Other specified abnormal immunological findings in serum

ICD-10-CM CodesR00–R99R70-R79R76

ICD-10-CM R76.89
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R76.89 is a billable ICD-10-CM diagnosis code for other specified abnormal immunological findings in serum. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established.

Code Identity

ICD-10-CM Code
R76.89
Billable Status
Yes — Valid for Submission
Code Describes
Other specified abnormal immunological findings in serum
Short Description
Other specified abnormal immunological findings in serum
Same as the full description in the CMS dataset.
Parent Code
Other specified abnormal immunological findings in serum

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR70-R79Abnormal findings on examination of blood, without diagnosis
CategoryR76Other abnormal immunological findings in serum
This CodeR76.89Other specified abnormal immunological findings in serum

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal blood test
  • Alanine aminotransferase above reference range
  • Alanine aminotransferase outside reference range
  • Antibody to Adenovirus detected
  • Antibody to Dependoparvovirus detected
  • Antibody to extractable nuclear antigen detected
  • Antibody to Human herpes simplex virus detected
  • Antibody to Lentivirus detected
  • Antibody to Retrovirus detected
  • Anticentromere antibody pattern
  • Anti-dengue IgG antibody detected
  • Anti-dengue IgM antibody detected
  • Anti-nuclear factor detected
  • Anti-nuclear factor weakly detected
  • Anti-streptolysin titer outside reference range
  • Bacterial antibody increase, paired specimens
  • Bacterial antibody titer - finding
  • Celiac disease detected by autoantibody screening
  • Complement level above reference range
  • Cytomegalovirus antibody detected in serum
  • Cytomegalovirus immunoglobulin M antibody detected in serum
  • Direct Coombs test positive
  • Epstein-Barr virus antibody detected in serum
  • Finding of Hepatitis A status
  • Finding of Hepatitis B status
  • Finding of Hepatitis C status
  • Finding of rubella status
  • Hepatitis A non-immune
  • Hepatitis B antibody present
  • Hepatitis B core antibody detected
  • Hepatitis B surface antigen detected
  • Hepatitis C antibody detected
  • Hepatitis C antibody detected with elevated alanine transaminase
  • Hepatitis C non-immune
  • Hepatitis C virus detected by enzyme-linked immunosorbent assay
  • Heterophile agglutin test abnormal
  • Homogeneous antinuclear antibody pattern
  • Human leukocyte antigen B27 detected
  • Indirect Coombs test positive
  • Jo-1 antibody detected
  • Legionella antibody detected
  • Lewis antibodies detected
  • Loss of isoantigens
  • Lupus antibody present
  • Mycoplasma titers outside reference range
  • Peripheral antinuclear antibody pattern
  • Reaginic antibodies detected
  • Rhesus antibody detected
  • Rubella non-immune
  • Rubella non-immune determined by serology
  • Rubella virus antibody not detected
  • Scl 70 antibody detected
  • Speckled antinuclear antibody pattern
  • Virus: serology - finding

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Raised level of immunoglobulins NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abnormal, abnormality, abnormalities
      • immunological findings
        • in serum
          • specified NEC
    • Elevated, elevation
      • immunoglobulin level
    • Positive
      • serology for syphilis
        • false

Code History & ChangesHistory

New Code R76.89 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement R76.89 replaces the following previously assigned code(s):

  • R76.8 - Other specified abnormal immunological findings in serum
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About R76.89Overview

Is R76.89 (Other specified abnormal immunological findings in serum) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other specified abnormal immunological findings in serum on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R76.89 group to?

When other specified abnormal immunological findings in serum is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R76.89 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the other specified abnormal immunological findings in serum is established, that condition takes the principal position instead.