2026 ICD-10-CM Diagnosis Code R22.43Localized swelling, mass and lump, lower limb, bilateral

ICD-10-CM Codes›R00–R99›R20-R23›R22

ICD-10-CM R22.43
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R22.43 is a billable ICD-10-CM diagnosis code for localized swelling, mass and lump, lower limb, bilateral. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 606 through 607. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Skin/Subcutaneous signs and symptoms.

Code Identity

ICD-10-CM Code
R22.43
Billable Status
Yes — Valid for Submission
Code Describes
Localized swelling, mass and lump, lower limb, bilateral
Short Description
Localized swelling, mass and lump, lower limb, bilateral
Same as the full description in the CMS dataset.
Parent Code
R22.4
Localized swelling, mass and lump, lower limb

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR20-R23Symptoms and signs involving the skin and subcutaneous tissue
CategoryR22Localized swelling, mass and lump of skin and subcutaneous tissue
This CodeR22.43Localized swelling, mass and lump, lower limb, bilateral

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral localized swelling of feet
  • Bilateral localized swelling of lower legs
  • Bilateral localized swelling of lower limbs
  • Bilateral localized swelling of toe of feet
  • Bilateral lower limb soft tissue mass
  • Bilateral mass of skin of feet
  • Bilateral mass of skin of lower legs
  • Bilateral mass of skin of lower limbs
  • Bilateral mass of skin of toe of feet
  • Bilateral mass of subcutaneous tissue of toe of feet
  • Bilateral nodule of subcutaneous tissue of feet
  • Bilateral nodule of subcutaneous tissue of lower legs
  • Bilateral nodule of subcutaneous tissue of toe of feet
  • Localized swelling of left foot
  • Localized swelling of left lower leg
  • Localized swelling of left lower limb
  • Localized swelling of right foot
  • Localized swelling of right lower leg
  • Localized swelling of right lower limb
  • Localized swelling of toe of left foot
  • Localized swelling of toe of right foot
  • Mass of muscle of bilateral lower limbs
  • Mass of muscle of left lower limb
  • Mass of muscle of right lower limb
  • Mass of skin of left lower leg
  • Mass of skin of right lower leg
  • Mass of skin of toe of left foot
  • Mass of skin of toe of right foot
  • Mass of subcutaneous tissue of bilateral feet
  • Mass of subcutaneous tissue of bilateral lower legs
  • Mass of subcutaneous tissue of bilateral lower limbs
  • Mass of subcutaneous tissue of left foot
  • Mass of subcutaneous tissue of left lower leg
  • Mass of subcutaneous tissue of right foot
  • Mass of subcutaneous tissue of right lower leg
  • Mass of subcutaneous tissue of toe of left foot
  • Mass of subcutaneous tissue of toe of right foot
  • Nodule of skin of bilateral feet
  • Nodule of skin of bilateral lower legs
  • Nodule of skin of bilateral lower limbs
  • Nodule of skin of foot
  • Nodule of skin of left foot
  • Nodule of skin of left lower limb
  • Nodule of skin of left toe
  • Nodule of skin of right foot
  • Nodule of skin of right lower limb
  • Nodule of skin of right toe
  • Nodule of skin of toe of bilateral feet
  • Nodule of skin of toe of left foot
  • Nodule of skin of toe of right foot
  • Nodule of subcutaneous tissue of bilateral lower limbs
  • Nodule of subcutaneous tissue of foot
  • Nodule of subcutaneous tissue of left foot
  • Nodule of subcutaneous tissue of left lower leg
  • Nodule of subcutaneous tissue of right foot
  • Nodule of subcutaneous tissue of right lower leg
  • Nodule of subcutaneous tissue of toe of left foot
  • Nodule of subcutaneous tissue of toe of right foot
  • Nodule on toe
  • Swelling of bilateral feet
  • Swelling of bilateral lower limbs
  • Swelling of left foot
  • Swelling of lower leg
  • Swelling of right foot
  • Swelling of toe of bilateral feet
  • Swelling of toe of left foot
  • Swelling of toe of right foot

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM014
Skin/Subcutaneous signs and symptoms
Default principal diagnosis: inpatient Yes · outpatient Yes

Convert R22.43 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
782.2 Local suprficial swellng
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R22.43Overview

Is R22.43 (Localized swelling, mass and lump, lower limb) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report localized swelling, mass and lump, lower limb, bilateral on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R22.43 group to?

When localized swelling, mass and lump, lower limb, bilateral is the principal diagnosis on an inpatient stay, it groups to MS-DRG 606, 607, with relative weights from 0.9064 to 1.5132 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R22.43 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the localized swelling, mass and lump, lower limb, bilateral is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R22.43?

Under the General Equivalence Mappings, localized swelling, mass and lump, lower limb, bilateral converts to ICD-9-CM 782.2 (local suprficial swellng). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.