2027 ICD-10-CM Diagnosis Code R22.43Localized swelling, mass and lump, lower limb, bilateral
ICD-10-CM Codes›R00–R99›R20-R23›R22
- Billable — Valid for Submission
- Not Chronic
R22.43 is a billable ICD-10-CM diagnosis code for localized swelling, mass and lump, lower limb, bilateral. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 606 through 607. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Skin/Subcutaneous signs and symptoms.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Bilateral localized swelling of feet
- Bilateral localized swelling of lower legs
- Bilateral localized swelling of lower limbs
- Bilateral localized swelling of toe of feet
- Bilateral lower limb soft tissue mass
- Bilateral mass of skin of feet
- Bilateral mass of skin of lower legs
- Bilateral mass of skin of lower limbs
- Bilateral mass of skin of toe of feet
- Bilateral mass of subcutaneous tissue of toe of feet
- Bilateral nodule of subcutaneous tissue of feet
- Bilateral nodule of subcutaneous tissue of lower legs
- Bilateral nodule of subcutaneous tissue of toe of feet
- Localized swelling of left foot
- Localized swelling of left lower leg
- Localized swelling of left lower limb
- Localized swelling of right foot
- Localized swelling of right lower leg
- Localized swelling of right lower limb
- Localized swelling of toe of left foot
- Localized swelling of toe of right foot
- Mass of muscle of bilateral lower limbs
- Mass of muscle of left lower limb
- Mass of muscle of right lower limb
- Mass of skin of left lower leg
- Mass of skin of right lower leg
- Mass of skin of toe of left foot
- Mass of skin of toe of right foot
- Mass of subcutaneous tissue of bilateral feet
- Mass of subcutaneous tissue of bilateral lower legs
- Mass of subcutaneous tissue of bilateral lower limbs
- Mass of subcutaneous tissue of left foot
- Mass of subcutaneous tissue of left lower leg
- Mass of subcutaneous tissue of right foot
- Mass of subcutaneous tissue of right lower leg
- Mass of subcutaneous tissue of toe of left foot
- Mass of subcutaneous tissue of toe of right foot
- Nodule of skin of bilateral feet
- Nodule of skin of bilateral lower legs
- Nodule of skin of bilateral lower limbs
- Nodule of skin of foot
- Nodule of skin of left foot
- Nodule of skin of left lower limb
- Nodule of skin of left toe
- Nodule of skin of right foot
- Nodule of skin of right lower limb
- Nodule of skin of right toe
- Nodule of skin of toe of bilateral feet
- Nodule of skin of toe of left foot
- Nodule of skin of toe of right foot
- Nodule of subcutaneous tissue of bilateral lower limbs
- Nodule of subcutaneous tissue of foot
- Nodule of subcutaneous tissue of left foot
- Nodule of subcutaneous tissue of left lower leg
- Nodule of subcutaneous tissue of right foot
- Nodule of subcutaneous tissue of right lower leg
- Nodule of subcutaneous tissue of toe of left foot
- Nodule of subcutaneous tissue of toe of right foot
- Nodule on toe
- Swelling of bilateral feet
- Swelling of bilateral lower limbs
- Swelling of left foot
- Swelling of lower leg
- Swelling of right foot
- Swelling of toe of bilateral feet
- Swelling of toe of left foot
- Swelling of toe of right foot
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to R22.43: its own notes plus those printed at R22, block R20-R23, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- subcutaneous nodules (localized)(superficial)
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Notes
General instructions on how these codes are used.
- This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
- Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
- The conditions and signs or symptoms included in categories R00-R94 consist of:
- (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
- (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
- (c) provisional diagnosis in a patient who failed to return for further investigation or care;
- (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
- (e) cases in which a more precise diagnosis was not available for any other reason;
- (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name R22.43, its category, or a range that includes it.
Applicable To 1
These notes mention R22.43.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Convert R22.43 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About R22.43Overview
What is the ICD-10 code for localized swelling, mass and lump, lower limb, bilateral?
The ICD-10-CM code for localized swelling, mass and lump, lower limb, bilateral is R22.43 (sometimes written as R2243). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is R22.43 (Localized swelling, mass and lump, lower limb) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report localized swelling, mass and lump, lower limb, bilateral on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does R22.43 group to?
When localized swelling, mass and lump, lower limb, bilateral is the principal diagnosis on an inpatient stay, it groups to MS-DRG 607, 606, with relative weights from 0.8772 to 1.5721 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R22.43 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the localized swelling, mass and lump, lower limb, bilateral is established, that condition takes the principal position instead.
Can R22.43 be reported with a code from R60?
Not as a rule. The Excludes1 note at R22, which applies to R22.43, lists "edema (R60.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
