2026 ICD-10-CM Diagnosis Code R22.40Localized swelling, mass and lump, unspecified lower limb

ICD-10-CM Codes›R00–R99›R20-R23›R22

ICD-10-CM R22.40
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R22.40 is a billable ICD-10-CM diagnosis code for localized swelling, mass and lump, unspecified lower limb. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 606 through 607. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Skin/Subcutaneous signs and symptoms.

Code Identity

ICD-10-CM Code
R22.40
Billable Status
Yes — Valid for Submission
Code Describes
Localized swelling, mass and lump, unspecified lower limb
Short Description
Localized swelling, mass and lump, unspecified lower limb
Same as the full description in the CMS dataset.
Parent Code
R22.4
Localized swelling, mass and lump, lower limb

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR20-R23Symptoms and signs involving the skin and subcutaneous tissue
CategoryR22Localized swelling, mass and lump of skin and subcutaneous tissue
This CodeR22.40Localized swelling, mass and lump, unspecified lower limb

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Foot swelling
  • Lump on thigh
  • Mass of ankle
  • Mass of foot
  • Mass of great toe
  • Mass of hip region
  • Mass of knee joint
  • Mass of lesser toe
  • Mass of lower limb
  • Mass of muscle of lower limb
  • Mass of psoas muscle
  • Mass of shin
  • Mass of tibia
  • Mass of toe
  • Nodule of skin of foot
  • Nodule of skin of lower limb
  • Nodule of subcutaneous tissue of foot
  • Nodule of subcutaneous tissue of lower limb
  • Nodule on toe
  • Sausage toe
  • Soft tissue swelling of ankle joint
  • Swelling of ankle joint
  • Swelling of lower leg
  • Swollen ankle region
  • Swollen calf
  • Toe swelling

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM014
Skin/Subcutaneous signs and symptoms
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Edema

Edema means swelling caused by fluid in your body's tissues. It usually occurs in the feet, ankles and legs, but it can involve your entire body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R22.40 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
782.2 Local suprficial swellng
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R22.40Overview

Is R22.40 (Localized swelling, mass and lump, lower limb) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report localized swelling, mass and lump, unspecified lower limb on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R22.40 group to?

When localized swelling, mass and lump, unspecified lower limb is the principal diagnosis on an inpatient stay, it groups to MS-DRG 606, 607, with relative weights from 0.9064 to 1.5132 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R22.40 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the localized swelling, mass and lump, unspecified lower limb is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R22.40?

Under the General Equivalence Mappings, localized swelling, mass and lump, unspecified lower limb converts to ICD-9-CM 782.2 (local suprficial swellng). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.