2027 ICD-10-CM Diagnosis Code R22.33Localized swelling, mass and lump, upper limb, bilateral

ICD-10-CM Codes›R00–R99›R20-R23›R22

ICD-10-CM R22.33
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R22.33 is a billable ICD-10-CM diagnosis code for localized swelling, mass and lump, upper limb, bilateral. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 606 through 607. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Skin/Subcutaneous signs and symptoms.

Code Identity

ICD-10-CM Code
R22.33
Billable Status
Yes — Valid for Submission
Code Describes
Localized swelling, mass and lump, upper limb, bilateral
Short Description
Localized swelling, mass and lump, upper limb, bilateral
Same as the full description in the CMS dataset.
Parent Code
R22.3
Localized swelling, mass and lump, upper limb

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR20-R23Symptoms and signs involving the skin and subcutaneous tissue
CategoryR22Localized swelling, mass and lump of skin and subcutaneous tissue
This CodeR22.33Localized swelling, mass and lump, upper limb, bilateral

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral localized swelling of finger of hands
  • Bilateral localized swelling of forearms
  • Bilateral localized swelling of hands
  • Bilateral localized swelling of thumbs
  • Bilateral localized swelling of upper limbs
  • Bilateral mass of axillary regions
  • Bilateral mass of skin of finger of hands
  • Bilateral mass of skin of forearms
  • Bilateral mass of skin of hands
  • Bilateral mass of skin of thumbs
  • Bilateral mass of skin of upper limbs
  • Bilateral mass of soft tissue of upper limbs
  • Bilateral mass of subcutaneous tissue of finger of hands
  • Bilateral mass of subcutaneous tissue of thumbs
  • Bilateral nodule of subcutaneous tissue of thumbs
  • Bilateral swelling of finger of hands
  • Bilateral swelling of upper limbs
  • Localized swelling of finger of left hand
  • Localized swelling of finger of right hand
  • Localized swelling of forearm
  • Localized swelling of left forearm
  • Localized swelling of left hand
  • Localized swelling of left thumb
  • Localized swelling of left upper limb
  • Localized swelling of right forearm
  • Localized swelling of right hand
  • Localized swelling of right thumb
  • Localized swelling of right upper limb
  • Mass of left axillary region
  • Mass of muscle of bilateral upper limbs
  • Mass of muscle of left upper limb
  • Mass of muscle of right upper limb
  • Mass of right axillary region
  • Mass of skin of finger of left hand
  • Mass of skin of finger of right hand
  • Mass of skin of left forearm
  • Mass of skin of left thumb
  • Mass of skin of right forearm
  • Mass of skin of right thumb
  • Mass of subcutaneous tissue of bilateral forearms
  • Mass of subcutaneous tissue of bilateral hands
  • Mass of subcutaneous tissue of bilateral upper limbs
  • Mass of subcutaneous tissue of finger of left hand
  • Mass of subcutaneous tissue of finger of right hand
  • Mass of subcutaneous tissue of left forearm
  • Mass of subcutaneous tissue of left thumb
  • Mass of subcutaneous tissue of right forearm
  • Mass of subcutaneous tissue of right thumb
  • Nodule of skin of bilateral forearms
  • Nodule of skin of bilateral hands
  • Nodule of skin of bilateral thumbs
  • Nodule of skin of bilateral upper limbs
  • Nodule of skin of finger of bilateral hands
  • Nodule of skin of finger of hand
  • Nodule of skin of finger of left hand
  • Nodule of skin of finger of right hand
  • Nodule of skin of forearm
  • Nodule of skin of left forearm
  • Nodule of skin of left hand
  • Nodule of skin of left thumb
  • Nodule of skin of left upper limb
  • Nodule of skin of right forearm
  • Nodule of skin of right hand
  • Nodule of skin of right thumb
  • Nodule of skin of right upper limb
  • Nodule of skin of thumb
  • Nodule of subcutaneous tissue of bilateral forearms
  • Nodule of subcutaneous tissue of bilateral hands
  • Nodule of subcutaneous tissue of bilateral upper limbs
  • Nodule of subcutaneous tissue of finger of bilateral hands
  • Nodule of subcutaneous tissue of finger of hand
  • Nodule of subcutaneous tissue of finger of left hand
  • Nodule of subcutaneous tissue of finger of right hand
  • Nodule of subcutaneous tissue of left forearm
  • Nodule of subcutaneous tissue of left hand
  • Nodule of subcutaneous tissue of left thumb
  • Nodule of subcutaneous tissue of right forearm
  • Nodule of subcutaneous tissue of right hand
  • Nodule of subcutaneous tissue of right thumb
  • Nodule on finger
  • Swelling of finger of left hand
  • Swelling of finger of right hand
  • Swollen thumb

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R22.33: its own notes plus those printed at R22, block R20-R23, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From R22 Localized swelling, mass and lump of skin and subcutaneous tissue applies to 12 codes
  • subcutaneous nodules (localized)(superficial)

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From R22 Localized swelling, mass and lump of skin and subcutaneous tissue applies to 12 codes
  • abnormal findings on diagnostic imaging (R90-R93)
  • edema (R60.-)
  • enlarged lymph nodes (R59.-)
  • localized adiposity (E65)
  • swelling of joint (M25.4-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block R20-R23 Symptoms and signs involving the skin and subcutaneous tissue applies to 26 codes
From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R22.33, its category, or a range that includes it.

Applicable To 1

These notes mention R22.33.

  • G71.038 Other limb girdle muscular dystrophy
    LGMD R22 collagen 6-related names R22, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM014
Skin/Subcutaneous signs and symptoms
Default principal diagnosis: inpatient Yes · outpatient Yes

Convert R22.33 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
782.2 Local suprficial swellng
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R22.33Overview

What is the ICD-10 code for localized swelling, mass and lump, upper limb, bilateral?

The ICD-10-CM code for localized swelling, mass and lump, upper limb, bilateral is R22.33 (sometimes written as R2233). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R22.33 (Localized swelling, mass and lump, upper limb) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report localized swelling, mass and lump, upper limb, bilateral on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R22.33 group to?

When localized swelling, mass and lump, upper limb, bilateral is the principal diagnosis on an inpatient stay, it groups to MS-DRG 607, 606, with relative weights from 0.8772 to 1.5721 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R22.33 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the localized swelling, mass and lump, upper limb, bilateral is established, that condition takes the principal position instead.

Can R22.33 be reported with a code from R60?

Not as a rule. The Excludes1 note at R22, which applies to R22.33, lists "edema (R60.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).