2026 ICD-10-CM Diagnosis Code N48.33Priapism, drug-induced

ICD-10-CM Codes›N00–N99›N40-N53›N48

ICD-10-CM N48.33
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

N48.33 is a billable ICD-10-CM diagnosis code for priapism, drug-induced. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 729 through 730. Coders also document this condition as priapism. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Other specified male genital disorders.

Code Identity

ICD-10-CM Code
N48.33
Billable Status
Yes — Valid for Submission
Code Describes
Priapism, drug-induced
Short Description
Priapism, drug-induced
Same as the full description in the CMS dataset.
Parent Code
N48.3
Priapism

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN40-N53Diseases of male genital organs
CategoryN48Other disorders of penis
This CodeN48.33Priapism, drug-induced

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Priapism
  • Priapism caused by drug

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Priapism
      • due to
        • drug

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR GEN016
Other specified male genital disorders
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Priapism

    a prolonged painful erection that may lasts hours and is not associated with sexual activity. it is seen in patients with sickle cell anemia, advanced malignancy, spinal trauma; and certain drug treatments.

  • Priapism

    persistent and usually painful erection that lasts for at least four hours in the absence of physical or psychological stimulation, which can be caused by hematologic disorders, including sickle cell disease and leukemia, spinal cord injuries, and medications.

Patient EducationClinical

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

The full article covers:

  • What is a drug interaction?
  • What are side effects?
  • What are drug allergies?
  • How can I stay safe when taking medicines?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert N48.33 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
607.3 Priapism
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About N48.33Overview

Is N48.33 (Priapism) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report priapism, drug-induced on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does N48.33 group to?

When priapism, drug-induced is the principal diagnosis on an inpatient stay, it groups to MS-DRG 729, 730, with relative weights from 0.6720 to 1.0587 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of N48.33?

Under the General Equivalence Mappings, priapism, drug-induced converts to ICD-9-CM 607.3 (priapism). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.