2026 ICD-10-CM Diagnosis Code M35.07Sjogren syndrome with central nervous system involvement

ICD-10-CM Codes›M00–M99›M30-M36›M35

ICD-10-CM M35.07
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

M35.07 is a billable ICD-10-CM diagnosis code for sjogren syndrome with central nervous system involvement. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 545 through 547. Coders also document this condition as central nervous system disorder due to Sjögren's syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative) and Systemic lupus erythematosus and connective tissue disorders.

Code Identity

ICD-10-CM Code
M35.07
Billable Status
Yes — Valid for Submission
Code Describes
Sjogren syndrome with central nervous system involvement
Short Description
Sjogren syndrome with central nervous system involvement
Same as the full description in the CMS dataset.
Parent Code
M35.0
Sjogren syndrome

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM30-M36Systemic connective tissue disorders
CategoryM35Other systemic involvement of connective tissue
This CodeM35.07Sjogren syndrome with central nervous system involvement

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Central nervous system disorder due to Sjögren's syndrome
  • Demyelination of central nervous system co-occurrent and due to Sjogren disease
  • Meningitis due to Sjögren syndrome
  • Myelitis due to Sjogren syndrome
  • Sjögren's syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Syndrome
      • Sjögren
        • with
          • central nervous system involvement

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient No · outpatient No
CCSR MUS024
Systemic lupus erythematosus and connective tissue disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Sjogren's Syndrome

Sjogren's syndrome, also called Sjogren's disease, is a chronic (long-lasting) autoimmune disease. When you have an autoimmune disease, your immune system attacks healthy tissues and organs by mistake. In Sjogren's syndrome, your immune system attacks the glands that make moisture in the eyes, mouth, and other parts of the body.

The full article covers:

  • What is Sjogren's syndrome?
  • What causes Sjogren's syndrome?
  • Who is more likely to develop Sjogren's syndrome?
  • What are the symptoms of Sjogren's syndrome?
  • How is Sjogren's syndrome diagnosed?
  • What are the treatments for Sjogren's syndrome?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement M35.07 replaces the following previously assigned code(s):

  • M35.09 - Sicca syndrome with other organ involvement
  • M35.09 - Sjogren syndrome with other organ involvement
FY 2022AddedAdded to the ICD-10-CM code setEffective October 1, 2021.
FY 2023–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About M35.07Overview

Is M35.07 (Sjogren syndrome) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report sjogren syndrome with central nervous system involvement on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does M35.07 group to?

When sjogren syndrome with central nervous system involvement is the principal diagnosis on an inpatient stay, it groups to MS-DRG 545, 546, 547, with relative weights from 0.8362 to 2.4817 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.