2024 ICD-10-CM Diagnosis Code M35.89
Other specified systemic involvement of connective tissue
- ICD-10-CM Code:
- M35.89
- ICD-10 Code for:
- Other specified systemic involvement of connective tissue
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Chronic
- Code Navigator:
M35.89 is a billable diagnosis code used to specify a medical diagnosis of other specified systemic involvement of connective tissue. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Antisynthetase syndrome
- Antisynthetase syndrome
- Antisynthetase syndrome
- Anti-synthetase syndrome due to dermatomyositis
- Antisynthetase syndrome due to polymyositis
- Autoimmune hypophysitis
- Collagen deficiency syndrome
- Cranial cerebrospinal fluid leak
- EMILIN-1-related connective tissue disease
- Eosinophilia myalgia syndrome
- Eosinophilia myalgia syndrome
- Eosinophilia-myalgia syndrome from tryptophan
- Hypophysitis
- Immunoglobulin G4 related aortitis
- Immunoglobulin G4 related disease
- Immunoglobulin G4 related disease
- Immunoglobulin G4 related disease
- Immunoglobulin G4 related eosinophilic angiocentric fibrosis
- Immunoglobulin G4 related hypophysitis
- Leak of cranial cerebrospinal fluid due to collagen deficiency syndrome
- Marden Walker syndrome
- Polyneuropathy in collagen malignant disease
- Satoyoshi syndrome
Clinical Classification
Clinical Category is Systemic lupus erythematosus and connective tissue disorders
- CCSR Category Code: MUS024
- Inpatient Default CCSR: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
- Outpatient Default CCSR: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Clinical Information
Autoimmune Hypophysitis
immune-mediated inflammation of the pituitary gland often associated with other autoimmune diseases (e.g., hashimoto disease; graves disease; and addison disease).Hypophysitis
inflammation of the pituitary gland.Pituitary Gland
a small, unpaired gland situated in the sella turcica. it is connected to the hypothalamus by a short stalk which is called the infundibulum.Autoimmune Hypophysitis|Lymphocytic Hypophysitis
an autoimmune condition affecting the pituitary gland, characterized by lymphocytic infiltration, commonly presenting with pituitary hormone deficiencies.Grade 1 Hypophysitis, CTCAE|Grade 1 Hypophysitis
asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicatedGrade 2 Hypophysitis, CTCAE|Grade 2 Hypophysitis
moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental adlGrade 3 Hypophysitis, CTCAE|Grade 3 Hypophysitis
severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care adlGrade 4 Hypophysitis, CTCAE|Grade 4 Hypophysitis
life-threatening consequences; urgent intervention indicatedGrade 5 Hypophysitis, CTCAE|Grade 5 Hypophysitis
deathHypophysitis
an inflammatory process in the pituitary gland.Hypophysitis, CTCAE|Hypophysitis
a disorder characterized by inflammation and cellular infiltration of the pituitary gland.Lymphocytic Neurohypophysitis
an autoimmune condition affecting the posterior pituitary gland, which is characterized by lymphocytic infiltration, and which often presents as diabetes insipidus.
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Disease, diseased - See Also: Syndrome;
- - collagen NOS (nonvascular) (vascular) - M35.9
- - specified NEC - M35.89
- - connective tissue, systemic (diffuse) - M35.9
- - specified NEC - M35.89
- - collagen NOS (nonvascular) (vascular) - M35.9
- - Eosinophilia-myalgia syndrome - M35.89
- - Syndrome - See Also: Disease;
- - eosinophilia-myalgia - M35.89
Replacement Code
M3589 replaces the following previously assigned ICD-10-CM code(s):
- M35.8 - Other specified systemic involvement of connective tissue
Patient Education
Connective Tissue Disorders
Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.
Over 200 disorders that impact connective tissue. There are different types:
- Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
- Autoimmune disorders, such as lupus and scleroderma
- Cancers, like some types of soft tissue sarcoma
Each disorder has its own symptoms and needs different treatment.
NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.