Other necrotizing vasculopathies (M31) ICD-10-CM
The M31 code range covers other necrotizing vasculopathies with 16 ICD-10-CM diagnosis codes. 13 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the M31 Range 16 codes · 13 billable
- M31 Other necrotizing vasculopathiesNon-billable
- M31.0 Hypersensitivity angiitis
- M31.1 Thrombotic microangiopathyNon-billable
- M31.10 Thrombotic microangiopathy, unspecified
- M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]
- M31.19 Other thrombotic microangiopathy
- M31.2 Lethal midline granuloma
- M31.3 Wegener's granulomatosisNon-billable
- M31.30 Wegener's granulomatosis without renal involvement
- M31.31 Wegener's granulomatosis with renal involvement
- M31.4 Aortic arch syndrome [Takayasu]
- M31.5 Giant cell arteritis with polymyalgia rheumatica
- M31.6 Other giant cell arteritis
- M31.7 Microscopic polyangiitis
- M31.8 Other specified necrotizing vasculopathies
- M31.9 Necrotizing vasculopathy, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the M31 range.
Giant Cell Arteritis
A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
Granulomatosis with Polyangiitis
A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN.
Microscopic Polyangiitis
A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.
Polymyalgia Rheumatica
A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
Systemic Vasculitis
A heterogeneous group of diseases characterized by inflammation and necrosis of the blood vessel walls.
About the M31 Code Range
The ICD-10 code M31 series is used to classify various specific types of necrotizing vasculopathies, which involve inflammation and destruction of blood vessel walls. These codes apply to diseases such as hypersensitivity angiitis, thrombotic microangiopathy, Wegener's granulomatosis, and giant cell arteritis, among others.
This group covers rare but significant conditions characterized by vessel wall damage and immune complex involvement. For example, code M31.0 refers to hypersensitivity angiitis—also called pulmonary renal syndrome or Goodpasture's syndrome—which involves immune reactions causing vessel inflammation. The codes M31.1 through M31.19 identify various forms of thrombotic microangiopathy, including those linked to hematopoietic stem cell transplantation. Codes M31.3 and its subtypes specify Wegener's granulomatosis (now known as granulomatosis with polyangiitis), a multisystem vasculitis often affecting kidneys and respiratory tract. The section also includes M31.4 for Takayasu's disease and M31.5 and M31.6 for different forms of giant cell arteritis. Medical coders can rely on these ICD-10 codes for precise documentation of these immune-mediated, necrotizing vascular diseases.
Questions About This Page
How many billable codes are in the M31 range?
Of the 16 codes in this range, 13 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the M31 range classify?
The range classifies other necrotizing vasculopathies. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
