2026 ICD-10-CM Diagnosis Code M35.04Sjogren syndrome with tubulo-interstitial nephropathy

ICD-10-CM Codes›M00–M99›M30-M36›M35

ICD-10-CM M35.04
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

M35.04 is a billable ICD-10-CM diagnosis code for sjogren syndrome with tubulo-interstitial nephropathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 545 through 547. Coders also document this condition as tubulointerstitial nephropathy due to Sjogren syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nephritis; nephrosis; renal sclerosis and Systemic lupus erythematosus and connective tissue disorders.

Code Identity

ICD-10-CM Code
M35.04
Billable Status
Yes — Valid for Submission
Code Describes
Sjogren syndrome with tubulo-interstitial nephropathy
Short Description
Sjogren syndrome with tubulo-interstitial nephropathy
Same as the full description in the CMS dataset.
Parent Code
M35.0
Sjogren syndrome

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM30-M36Systemic connective tissue disorders
CategoryM35Other systemic involvement of connective tissue
This CodeM35.04Sjogren syndrome with tubulo-interstitial nephropathy

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Tubulointerstitial nephropathy due to Sjogren syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Renal tubular acidosis in sicca syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Nephritis, nephritic(albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)
      • tubulo-interstitial (in)
        • Sjögren's syndrome
    • Pyelonephritis
      • in (due to)
        • Sjögren's disease
    • Syndrome
      • Sjögren
        • with
          • renal tubular acidosis
    • Syndrome
      • Sjögren
        • with
          • tubulo-interstitial nephropathy

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN001
Nephritis; nephrosis; renal sclerosis
Default principal diagnosis: inpatient No · outpatient No
CCSR MUS024
Systemic lupus erythematosus and connective tissue disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M35.04 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
710.2 Sicca syndrome
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
583.81 Nephritis NOS in oth dis
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2021No changes
FY 2022RevisedCode revised
FY 2023–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About M35.04Overview

Is M35.04 (Sjogren syndrome) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report sjogren syndrome with tubulo-interstitial nephropathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does M35.04 group to?

When sjogren syndrome with tubulo-interstitial nephropathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 545, 546, 547, with relative weights from 0.8362 to 2.4817 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of M35.04?

Under the General Equivalence Mappings, sjogren syndrome with tubulo-interstitial nephropathy converts to ICD-9-CM 710.2 (sicca syndrome) and 583.81 (nephritis NOS in oth dis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.