2026 ICD-10-CM Diagnosis Code F33.3Major depressive disorder, recurrent, severe with psychotic symptoms

ICD-10-CM Codes›F01–F99›F30-F39›F33

ICD-10-CM F33.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

F33.3 is a billable ICD-10-CM diagnosis code for major depressive disorder, recurrent, severe with psychotic symptoms. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Depressive disorders.

Code Identity

ICD-10-CM Code
F33.3
Billable Status
Yes — Valid for Submission
Code Describes
Major depressive disorder, recurrent, severe with psychotic symptoms
Short Description
Major depressv disorder, recurrent, severe w psych symptoms
Parent Code
F33
Major depressive disorder, recurrent

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF30-F39Mood [affective] disorders
CategoryF33Major depressive disorder, recurrent
This CodeF33.3Major depressive disorder, recurrent, severe with psychotic symptoms

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Major depression with psychotic features
  • Recurrent major depressive disorder with atypical features
  • Recurrent major depressive disorder with catatonic features
  • Recurrent major depressive episodes
  • Recurrent major depressive episodes, severe, with psychosis
  • Severe major depression with psychotic features
  • Severe major depression with psychotic features, mood-congruent
  • Severe major depression with psychotic features, mood-incongruent
  • Severe recurrent major depression
  • Severe recurrent major depression with psychotic features
  • Severe recurrent major depression with psychotic features, mood-congruent
  • Severe recurrent major depression with psychotic features, mood-incongruent

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Endogenous depression with psychotic symptoms
  • Major depressive disorder, recurrent, with psychotic features
  • Recurrent severe episodes of major depression with mood-congruent psychotic symptoms
  • Recurrent severe episodes of major depression with mood-incongruent psychotic symptoms
  • Recurrent severe episodes of major depression with psychotic symptoms
  • Recurrent severe episodes of psychogenic depressive psychosis
  • Recurrent severe episodes of psychotic depression
  • Recurrent severe episodes of reactive depressive psychosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Depression(acute) (mental)
      • endogenous (without psychotic symptoms)
        • with psychotic symptoms
    • Depression(acute) (mental)
      • psychotic (single episode)
        • recurrent
    • Depression(acute) (mental)
      • vital (recurrent) (without psychotic symptoms)
        • with psychotic symptoms
    • Disorder(of)
      • depressive
        • major
          • recurrent
            • with psychotic features
    • Disorder(of)
      • depressive
        • recurrent
          • current episode
            • severe (without psychotic symptoms)
              • with psychotic symptoms
    • Psychosis, psychotic
      • reactive (brief) (transient) (emotional stress) (psychological trauma)
        • depressive
          • recurrent

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD002
Depressive disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Depression

Depression is more than a feeling of being sad or irritable for a few days. It's a serious mood disorder. As one of the most common mental disorders in the United States, depression can affect how you think, feel, and your everyday life.

The full article covers:

  • What is depression?
  • What are the different types of depression?
  • What causes depression?
  • Who is at risk of depression?
  • What are the symptoms of depression?
  • How is depression diagnosed?
  • What are the treatments for depression?
  • Can depression be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert F33.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
296.34 Rec depr psych-psychotic
Approximate The match is approximate rather than exact.
ICD-9-CM
298.0 React depress psychosis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About F33.3Overview

Is F33.3 (Major depressive disorder, recurrent) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report major depressive disorder, recurrent, severe with psychotic symptoms on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of F33.3?

Under the General Equivalence Mappings, major depressive disorder, recurrent, severe with psychotic symptoms converts to ICD-9-CM 296.34 (rec depr psych-psychotic) and 298.0 (react depress psychosis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.