Major depressive disorder, recurrent (F33) ICD-10-CM
The F33 code range covers major depressive disorder, recurrent with 11 ICD-10-CM diagnosis codes. 9 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- recurrent episodes of depressive reaction
- recurrent episodes of endogenous depression
- recurrent episodes of major depression
- recurrent episodes of psychogenic depression
- recurrent episodes of reactive depression
- recurrent episodes of seasonal affective disorder
- recurrent episodes of seasonal depressive disorder
- recurrent episodes of vital depression
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the F33 Range 11 codes · 9 billable
- F33 Major depressive disorder, recurrentNon-billable
- F33.0 Major depressive disorder, recurrent, mild
- F33.1 Major depressive disorder, recurrent, moderate
- F33.2 Major depressive disorder, recurrent severe without psychotic features
- F33.3 Major depressive disorder, recurrent, severe with psychotic symptoms
- F33.4 Major depressive disorder, recurrent, in remissionNon-billable
- F33.40 Major depressive disorder, recurrent, in remission, unspecified
- F33.41 Major depressive disorder, recurrent, in partial remission
- F33.42 Major depressive disorder, recurrent, in full remission
- F33.8 Other recurrent depressive disorders
- F33.9 Major depressive disorder, recurrent, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the F33 range.
Major Depressive Disorder
Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every day; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
About the F33 Code Range
Recurrent major depressive disorder is major depression that returns. This category sits within mood disorders.
The subdivisions separate mild, moderate, and severe forms. Severe depression splits by whether psychotic symptoms are present. Remission has separate codes for partial, full, and unspecified remission. Other recurrent depressive disorders and recurrent major depressive disorder with unspecified severity have their own subdivisions.
Questions About This Page
How many billable codes are in the F33 range?
Of the 11 codes in this range, 9 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the F33 range classify?
The range classifies major depressive disorder, recurrent. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
