2027 ICD-10-CM Diagnosis Code F33Major depressive disorder, recurrent

ICD-10-CM Codes›F01–F99›F30-F39›F33

ICD-10-CM F33
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

F33 is a non-billable ICD-10-CM category code for major depressive disorder, recurrent, so it cannot be submitted on claims. Use a more specific code from this category instead, such as F33.0, F33.1, F33.2, and F33.3.

Code Identity

ICD-10-CM Code
F33
Billable Status
No — Non-Billable Category
Code Describes
Major depressive disorder, recurrent
Short Description
Major depressive disorder, recurrent
Same as the full description in the CMS dataset.
Chapter
F30-F39
Mood [affective] disorders

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF30-F39Mood [affective] disorders
CategoryF33Major depressive disorder, recurrent
This CodeF33Major depressive disorder, recurrent

Specific Coding for Major depressive disorder, recurrentOverview

Non-specific codes like F33 require more characters. Use one of these billable codes instead:

  • Use F33.0 for Major depressive disorder, recurrent, mild

  • Use F33.1 for Major depressive disorder, recurrent, moderate

  • Use F33.2 for Major depressive disorder, recurrent severe without psychotic features

  • Use F33.3 for Major depressive disorder, recurrent, severe with psychotic symptoms

  • F33.4 for Major depressive disorder, recurrent, in remission

  • Use F33.40 for Major depressive disorder, recurrent, in remission, unspecified

  • Use F33.41 for Major depressive disorder, recurrent, in partial remission

  • Use F33.42 for Major depressive disorder, recurrent, in full remission

  • Use F33.8 for Other recurrent depressive disorders

  • Use F33.9 for Major depressive disorder, recurrent, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to F33: its own notes plus those printed at Chapter 5. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

On F33 itself
  • recurrent episodes of depressive reaction
  • recurrent episodes of endogenous depression
  • recurrent episodes of major depression
  • recurrent episodes of psychogenic depression
  • recurrent episodes of reactive depression
  • recurrent episodes of seasonal affective disorder
  • recurrent episodes of seasonal depressive disorder
  • recurrent episodes of vital depression
From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • disorders of psychological development

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name F33, its category, or a range that includes it.

Excludes1 5

These codes carry an Excludes1 note naming F33: they are not reported together with it, unless the two conditions are unrelated.

  • F30 Manic episode
    major depressive disorder, recurrent (F33.-)
  • F31 Bipolar disorder
    major depressive disorder, recurrent (F33.-)
  • F32 Depressive episode
    recurrent depressive disorder (F33.-)
  • R40.1 Stupor
    depressive stupor (F31.-, F32.-, F33.-)
  • R53.8 Other malaise and fatigue
    exhaustion and fatigue due to recurrent depressive episode (F33-)

Excludes2 7

These codes carry an Excludes2 note naming F33: its condition is not part of those codes, and both may be reported when the patient has both.

  • F42 Obsessive-compulsive disorder
    obsessive-compulsive symptoms occurring in depression (F32.-, F33.-)
  • F44.2 Dissociative stupor
    depressive stupor (F32, F33)
  • F63.2 Kleptomania
    depressive disorder with stealing (F31.-, F32.-, F33.-)
  • F06.3 Mood disorder due to known physiological condition
    mood disorders, not due to known physiological condition or unspecified (F30-F39) names F30-F39, which includes this code
  • F90 Attention-deficit hyperactivity disorders
    mood [affective] disorders (F30-F39) names F30-F39, which includes this code
  • F91 Conduct disorders
    mood [affective] disorders (F30-F39) names F30-F39, which includes this code
  • F93.0 Separation anxiety disorder of childhood
    mood [affective] disorders (F30-F39) names F30-F39, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical InformationClinical

  • Major Depressive Disorder

    disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. symptoms include: depressed mood most of the day, nearly every day; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (dsm-5)

Patient EducationClinical

Depression

Depression is more than a feeling of being sad or irritable for a few days. It's a serious mood disorder. As one of the most common mental disorders in the United States, depression can affect how you think, feel, and your everyday life.

The full article covers:

  • What is depression?
  • What are the different types of depression?
  • What causes depression?
  • Who is at risk of depression?
  • What are the symptoms of depression?
  • How is depression diagnosed?
  • What are the treatments for depression?
  • Can depression be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About F33Overview

What is the ICD-10 code for major depressive disorder, recurrent?

F33 is the ICD-10-CM category for major depressive disorder, recurrent, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is F33 (Major depressive disorder, recurrent) a billable code?

No. This is a category header that groups the codes for major depressive disorder, recurrent, and headers cannot be submitted on claims. Claims for major depressive disorder, recurrent need a more specific code from this category, such as F33.0, F33.1, and F33.2.

Can F33 be reported with a code from F31?

Not as a rule. The Excludes1 note on F33 lists "bipolar disorder (F31.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).