2026 ICD-10-CM Diagnosis Code D47.4Osteomyelofibrosis

ICD-10-CM Codes›C00–D49›D37-D48›D47

ICD-10-CM D47.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D47.4 is a billable ICD-10-CM diagnosis code for osteomyelofibrosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as myelofibrosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

For Medicare Advantage risk adjustment, D47.4 maps to CMS-HCC Category 19 (Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers) under the V28 model, adding a risk factor of about 1.798 for a community, non-dual, aged beneficiary in payment year 2026.

Code Identity

ICD-10-CM Code
D47.4
Billable Status
Yes — Valid for Submission
Code Describes
Osteomyelofibrosis
Short Description
Osteomyelofibrosis
Same as the full description in the CMS dataset.
Parent Code
Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD47Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
This CodeD47.4Osteomyelofibrosis

Medicare Risk Adjustment (HCC)Billing

D47.4 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.

CMS-HCC V28 Category (Payment Model)
HCC 19— Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers
Payment HCC · PY 2026 one of 68 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+1.798
community, non-dual, aged · ranges 0.957–1.989 across segments
Hierarchy
Superseded by HCC 17 and HCC 18
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 46
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 46 · ESRD (V21): HCC 46 · ESRD (V24): HCC 46
ESRD V21 weights: 0.180 dialysis, 0.766–1.325 functioning graft · ESRD V24 weights: 0.223 dialysis, 0.748–4.064 functioning graft
Part D (RxHCC)
RxHCC 16 — Multiple Myeloma and Other Hematologic Cancers
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Myelofibrosis
  • Primary myelofibrosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Chronic idiopathic myelofibrosis
  • Myelofibrosis (idiopathic) (with myeloid metaplasia)
  • Myelosclerosis (megakaryocytic) with myeloid metaplasia
  • Secondary myelofibrosis in myeloproliferative disease

Type 1 Excludes

  • acute myelofibrosis C94.4

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Primary Myelofibrosis

    a de novo myeloproliferation arising from an abnormal stem cell. it is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by cytokines arising from the abnormal clone.
  • Cytokines

    non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. they differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. they generally act locally in a paracrine or autocrine rather than endocrine manner.

Patient EducationClinical

Bone Marrow Diseases

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D47.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
289.89 Blood diseases NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D47.4Overview

What is the ICD-10 code for osteomyelofibrosis?

The ICD-10-CM code for osteomyelofibrosis is D47.4 (sometimes written as D474). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is D47.4 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report osteomyelofibrosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D47.4 group to?

When osteomyelofibrosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D47.4?

Under the General Equivalence Mappings, osteomyelofibrosis converts to ICD-9-CM 289.89 (blood diseases NEC). The mapping is approximate, so confirm the match fits the documentation.

What HCC is D47.4?

D47.4 (osteomyelofibrosis) maps to CMS-HCC Category 19 (Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers), commonly written as HCC 19, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 46 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 16.

Does D47.4 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, D47.4 adds a risk adjustment factor of about 1.798 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.957 to 1.989 depending on the payment segment). A more severe related category (HCC 17 and HCC 18) supersedes it when both are reported. See the full factor table on the HCC 19 category page.