2026 ICD-10-CM Diagnosis Code D47.4Osteomyelofibrosis

ICD-10-CM Codes›C00–D49›D37-D48›D47

ICD-10-CM D47.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D47.4 is a billable ICD-10-CM diagnosis code for osteomyelofibrosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as myelofibrosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D47.4
Billable Status
Yes — Valid for Submission
Code Describes
Osteomyelofibrosis
Short Description
Osteomyelofibrosis
Same as the full description in the CMS dataset.
Parent Code
D47
Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD47Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
This CodeD47.4Osteomyelofibrosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Myelofibrosis
  • Primary myelofibrosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Chronic idiopathic myelofibrosis
  • Myelofibrosis (idiopathic) (with myeloid metaplasia)
  • Myelosclerosis (megakaryocytic) with myeloid metaplasia
  • Secondary myelofibrosis in myeloproliferative disease

Type 1 Excludes

  • acute myelofibrosis C94.4

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Myelofibrosis
      • with myeloid metaplasia
    • Myelofibrosis
      • idiopathic (chronic)
    • Myelofibrosis
      • secondary
        • in myeloproliferative disease
    • Myelosclerosis
      • with myeloid metaplasia
    • Myelosclerosis
      • megakaryocytic
    • Myelosclerosis
      • megakaryocytic
        • with myeloid metaplasia
    • Osteomyelofibrosis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Primary Myelofibrosis

    a de novo myeloproliferation arising from an abnormal stem cell. it is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by cytokines arising from the abnormal clone.

  • Cytokines

    non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. they differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. they generally act locally in a paracrine or autocrine rather than endocrine manner.

Patient EducationClinical

Bone Marrow Diseases

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D47.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
289.89 Blood diseases NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D47.4Overview

Is D47.4 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report osteomyelofibrosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D47.4 group to?

When osteomyelofibrosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D47.4?

Under the General Equivalence Mappings, osteomyelofibrosis converts to ICD-9-CM 289.89 (blood diseases NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.