2027 ICD-10-CM Diagnosis Code C74.01Malignant neoplasm of cortex of right adrenal gland

ICD-10-CM Codes›C00–D49›C73-C75›C74

ICD-10-CM C74.01
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

C74.01 is a billable ICD-10-CM diagnosis code for malignant neoplasm of cortex of right adrenal gland. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 25 closely related codes. Coders also document this condition as malignant neoplasm of adrenal cortex. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Endocrine system cancers - adrenocortical.

For Medicare Advantage risk adjustment, C74.01 maps to CMS-HCC Category 22 (Bladder, Colorectal, and Other Cancers) under the V28 model, adding a risk factor of about 0.363 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
C74.01
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of cortex of right adrenal gland
Short Description
Malignant neoplasm of cortex of right adrenal gland
Same as the full description in the CMS dataset.
Parent Code
Malignant neoplasm of cortex of adrenal gland

Code Classification

ChapterC00–D49Neoplasms
SectionC73-C75Malignant neoplasms of thyroid and other endocrine glands
CategoryC74Malignant neoplasm of adrenal gland
This CodeC74.01Malignant neoplasm of cortex of right adrenal gland

Medicare Risk Adjustment (HCC)Billing

C74.01 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 22— Bladder, Colorectal, and Other Cancers
Payment HCC · PY 2027 one of 126 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.363
community, non-dual, aged · ranges 0.314–0.410 across segments
Hierarchy
Superseded by HCC 17, HCC 18, HCC 19, HCC 20, and HCC 21
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 10
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 10 · ESRD (V21): HCC 10 · ESRD (V24): HCC 10
ESRD V21 weights: 0.136 dialysis, 0.451–0.668 functioning graft · ESRD V24 weights: 0.111 dialysis, 0.467–0.780 functioning graft
Part D (RxHCC)
RxHCC 22 — Prostate, Breast, Bladder, and Other Cancers and Tumors
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Malignant neoplasm of adrenal cortex
  • Primary malignant neoplasm of adrenal cortex
  • Primary malignant neoplasm of right adrenal cortex

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to C74.01: its own notes plus those printed at Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name C74.01, its category, or a range that includes it.

Applicable To 2

These notes mention C74.01.

  • Z85.8 Personal history of malignant neoplasms of other organs and systems
    Conditions classifiable to C00-C14, C40-C49, C69-C75, C7A.098, C76-C79 names C69-C75, which includes this code
  • Z85.85 Personal history of malignant neoplasm of endocrine glands
    Conditions classifiable to C73-C75 names C73-C75, which includes this code

Excludes1 1

These codes carry an Excludes1 note naming C74.01: they are not reported together with it, unless the two conditions are unrelated.

  • C75 Malignant neoplasm of other endocrine glands and related structures
    malignant neoplasm of adrenal gland (C74.-) names C74.-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO053
Endocrine system cancers - adrenocortical
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Malignant Adrenal Gland Neoplasm

    a primary or metastatic malignant neoplasm that affects the adrenal gland.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
adrenal › cortexC74.0C79.7D09.3D35.0D44.1D49.7
cortex › adrenalC74.0C79.7D09.3D35.0D44.1D49.7
suprarenal › cortexC74.0C79.7D09.3D35.0D44.1D49.7

Patient EducationClinical

Adrenal Gland Cancer

Your adrenal, or suprarenal, glands are located on the top of each kidney. These glands produce hormones that you can't live without, including sex hormones and cortisol, which helps you respond to stress and has many other functions.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C74.01 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
194.0 Malign neopl adrenal
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About C74.01Overview

What is the ICD-10 code for malignant neoplasm of cortex of right adrenal gland?

The ICD-10-CM code for malignant neoplasm of cortex of right adrenal gland is C74.01 (sometimes written as C7401). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is C74.01 (Malignant neoplasm of cortex of adrenal gland) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of cortex of right adrenal gland on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does C74.01 group to?

When malignant neoplasm of cortex of right adrenal gland is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.

Is C74.01 a CC or MCC?

CMS lists C74.01 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 25 closely related codes in its exclusion list.

What is the ICD-9 equivalent of C74.01?

Under the General Equivalence Mappings, malignant neoplasm of cortex of right adrenal gland converts to ICD-9-CM 194.0 (malign neopl adrenal). The mapping is approximate, so confirm the match fits the documentation.

What HCC is C74.01?

C74.01 (malignant neoplasm of cortex of right adrenal gland) maps to CMS-HCC Category 22 (Bladder, Colorectal, and Other Cancers), commonly written as HCC 22, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 10 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 22.

Does C74.01 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, C74.01 adds a risk adjustment factor of about 0.363 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.314 to 0.410 depending on the payment segment). A more severe related category (HCC 17, HCC 18, HCC 19, HCC 20, and HCC 21) supersedes it when both are reported. See the full factor table on the HCC 22 category page.