2026 ICD-10-CM Diagnosis Code B56.9African trypanosomiasis, unspecified

ICD-10-CM Codes›A00–B99›B50-B64›B56

ICD-10-CM B56.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B56.9 is a billable ICD-10-CM diagnosis code for african trypanosomiasis, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 867 through 869. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
B56.9
Billable Status
Yes — Valid for Submission
Code Describes
African trypanosomiasis, unspecified
Short Description
African trypanosomiasis, unspecified
Same as the full description in the CMS dataset.
Parent Code
B56
African trypanosomiasis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB50-B64Protozoal diseases
CategoryB56African trypanosomiasis
This CodeB56.9African trypanosomiasis, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • African trypanosomiasis
  • African trypanosomiasis affecting skin
  • Encephalitis caused by Trypanosoma brucei
  • Infection by Trypanosoma brucei brucei
  • Infection by Trypanosoma suis
  • Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense
  • Trypanosomiasis
  • Trypanosomiasis affecting skin
  • Trypanosomiasis with encephalitis
  • Trypanosomiasis with meningitis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Sleeping sickness NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • African
      • sleeping sickness
    • African
      • trypanosomiasis
    • Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
      • in (due to)
        • trypanosomiasis
          • African
    • Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
      • in (due to)
        • trypanosomiasis
          • African
            • with behavioral disturbance
    • Encephalitis(chronic) (hemorrhagic) (idiopathic) (nonepidemic) (spurious) (subacute)
      • in (due to)
        • African trypanosomiasis
    • Meningitis(basal) (basic) (brain) (cerebral) (cervical) (congestive) (diffuse) (hemorrhagic) (infantile) (membranous) (metastatic) (nonspecific) (pontine) (progressive) (simple) (spinal) (subacute) (sympathetic) (toxic)
      • in (due to)
        • African trypanosomiasis
    • Sickness
      • sleeping (African)
    • Sickness
      • sleeping (African)
        • by Trypanosoma
    • Trypanosomiasis
      • African
    • Trypanosomiasis
      • where
        • African trypanosomiasis is prevalent

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Chagas Cardiomyopathy

    a disease of the cardiac muscle developed subsequent to the initial protozoan infection by trypanosoma cruzi. after infection, less than 10% develop acute illness such as myocarditis (mostly in children). the disease then enters a latent phase without clinical symptoms until about 20 years later. myocardial symptoms of advanced chagas disease include conduction defects (heart block) and cardiomegaly.

  • Chagas Disease

    infection with the protozoan parasite trypanosoma cruzi, a form of trypanosomiasis endemic in central and south america. it is named after the brazilian physician carlos chagas, who discovered the parasite. infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of parasympathetic ganglia; chagas cardiomyopathy; and dysfunction of the esophagus or colon.

  • Trypanosomiasis

    infection with protozoa of the genus trypanosoma.

  • Trypanosomiasis, African

    a disease endemic among people and animals in central africa. it is caused by various species of trypanosomes, particularly t. gambiense and t. rhodesiense. its second host is the tsetse fly. involvement of the central nervous system produces african sleeping sickness. nagana is a rapidly fatal trypanosomiasis of horses and other animals.

  • Trypanosomiasis, Bovine

    infection in cattle caused by various species of trypanosomes.

  • Trypanosoma

    a genus of flagellate protozoans found in the blood and lymph of vertebrates and invertebrates, both hosts being required to complete the life cycle.

  • Tsetse Flies

    bloodsucking flies of the genus glossina, found primarily in equatorial africa. several species are intermediate hosts of trypanosomes.

Patient EducationClinical

Parasitic Diseases

Parasites are living things that use other living things - like your body - for food and a place to live. You can get them from contaminated food or water, a bug bite, or sexual contact. Some parasitic diseases are easily treated and some are not.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B56.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
086.5 African trypanosoma NOS
Approximate The match is approximate rather than exact.
ICD-9-CM
086.9 Trypanosomiasis NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B56.9Overview

Is B56.9 (African trypanosomiasis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report african trypanosomiasis, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B56.9 group to?

When african trypanosomiasis, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 868, 869, with relative weights from 0.7297 to 2.0932 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of B56.9?

Under the General Equivalence Mappings, african trypanosomiasis, unspecified converts to ICD-9-CM 086.5 (african trypanosoma NOS) and 086.9 (trypanosomiasis NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.