2027 ICD-10-CM Diagnosis Code B56.9African trypanosomiasis, unspecified

ICD-10-CM Codes›A00–B99›B50-B64›B56

ICD-10-CM B56.9
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

B56.9 is a billable ICD-10-CM diagnosis code for african trypanosomiasis, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 867 through 869. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 69 closely related codes. Coders also document this condition as african trypanosomiasis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
B56.9
Billable Status
Yes — Valid for Submission
Code Describes
African trypanosomiasis, unspecified
Short Description
African trypanosomiasis, unspecified
Same as the full description in the CMS dataset.
Parent Code
B56
African trypanosomiasis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB50-B64Protozoal diseases
CategoryB56African trypanosomiasis
This CodeB56.9African trypanosomiasis, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • African trypanosomiasis
  • African trypanosomiasis affecting skin
  • Encephalitis caused by Trypanosoma brucei
  • Infection by Trypanosoma brucei brucei
  • Infection by Trypanosoma suis
  • Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense
  • Trypanosomiasis
  • Trypanosomiasis affecting skin
  • Trypanosomiasis with encephalitis
  • Trypanosomiasis with meningitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to B56.9: its own notes plus those printed at block B50-B64 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Sleeping sickness NOS

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block B50-B64 Protozoal diseases applies to 57 codes
  • amebiasis (A06.-)
  • other protozoal intestinal diseases (A07.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name B56.9, its category, or a range that includes it.

Applicable To 1

These notes mention B56.9.

  • O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium
    Conditions in B50-B64 names B50-B64, which includes this code

Code First 2

These codes say to code first a condition named in the note, and B56.9 is one of the conditions named.

  • F02 Dementia in other diseases classified elsewhere
    trypanosomiasis (B56.-, B57.-) names B56.-, which includes this code
  • G02 Meningitis in other infectious and parasitic diseases classified elsewhere
    African trypanosomiasis (B56.-) names B56.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Trypanosomiasis, African

    a disease endemic among people and animals in central africa. it is caused by various species of trypanosomes, particularly t. gambiense and t. rhodesiense. its second host is the tsetse fly. involvement of the central nervous system produces african sleeping sickness. nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Patient EducationClinical

Parasitic Diseases

Parasites are living things that use other living things - like your body - for food and a place to live. You can get them from contaminated food or water, a bug bite, or sexual contact. Some parasitic diseases are easily treated and some are not.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B56.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
086.5 African trypanosoma NOS
Approximate The match is approximate rather than exact.
ICD-9-CM
086.9 Trypanosomiasis NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About B56.9Overview

What is the ICD-10 code for african trypanosomiasis, unspecified?

The ICD-10-CM code for african trypanosomiasis, unspecified is B56.9 (sometimes written as B569). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is B56.9 (African trypanosomiasis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report african trypanosomiasis, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does B56.9 group to?

When african trypanosomiasis, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 869, 868, with relative weights from 0.6784 to 2.1855 depending on complications. Higher weights mean higher Medicare reimbursement.

Is B56.9 a CC or MCC?

CMS lists B56.9 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 69 closely related codes in its exclusion list.

Can B56.9 be reported with a code from A06?

Not as a rule. The Excludes1 note at block B50-B64, which applies to B56.9, lists "amebiasis (A06.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).