2027 ICD-10-CM Diagnosis Code B27.19Cytomegaloviral mononucleosis with other complication
ICD-10-CM Codes›A00–B99›B25-B34›B27
- Billable — Valid for Submission
- Not Chronic
B27.19 is a billable ICD-10-CM diagnosis code for cytomegaloviral mononucleosis with other complication. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 865 through 866. Coders also document this condition as large liver due to infectious mononucleosis caused by Cytomegalovirus. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Viral infection.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Large liver due to infectious mononucleosis caused by Cytomegalovirus
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to B27.19: its own notes plus those printed at B27 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- glandular fever
- monocytic angina
- Pfeiffer's disease
- diseases generally recognized as communicable or transmissible
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Hepatomegaly in cytomegaloviral mononucleosis
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify resistance to antimicrobial drugs (Z16.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name B27.19, its category, or a range that includes it.
Applicable To 1
These notes mention B27.19.
- O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
Excludes1 5
These codes carry an Excludes1 note naming B27.19: they are not reported together with it, unless the two conditions are unrelated.
- B25 Cytomegaloviral diseasecytomegaloviral mononucleosis (B27.1-) names B27.1-, which includes this code
- D72.821 Monocytosis (symptomatic)infectious mononucleosis (B27.-) names B27.-, which includes this code
- G02 Meningitis in other infectious and parasitic diseases classified elsewhereinfectious mononucleosis complicated by meningitis (B27.- with fifth character 2) names B27.-, which includes this code
- J02.8 Acute pharyngitis due to other specified organismsacute pharyngitis due to infectious mononucleosis (B27.-) names B27.-, which includes this code
- G63 Polyneuropathy in diseases classified elsewhere
Code First 1
These codes say to code first a condition named in the note, and B27.19 is one of the conditions named.
- K77 Liver disorders in diseases classified elsewhere
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Infectious Mononucleosis
a common, acute infection usually caused by the epstein-barr virus (herpesvirus 4, human). there is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis.
Patient EducationClinical
Infectious Mononucleosis
Infectious mononucleosis (mono) is a disease caused by viruses.The most common cause is the Epstein-Barr virus (EBV). Mono is contagious, which means it can spread from person to person. It is common among teenagers and young adults, especially college students.
The full article covers:
- What is infectious mononucleosis (mono)?
- What causes infectious mononucleosis (mono)?
- What are the symptoms of infectious mononucleosis (mono)?
- How is infectious mononucleosis (mono) diagnosed?
- What are the treatments for infectious mononucleosis (mono)?
- Can infectious mononucleosis (mono) be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert B27.19 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About B27.19Overview
What is the ICD-10 code for cytomegaloviral mononucleosis with other complication?
The ICD-10-CM code for cytomegaloviral mononucleosis with other complication is B27.19 (sometimes written as B2719). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is B27.19 (Cytomegaloviral mononucleosis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report cytomegaloviral mononucleosis with other complication on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does B27.19 group to?
When cytomegaloviral mononucleosis with other complication is the principal diagnosis on an inpatient stay, it groups to MS-DRG 866, 865, with relative weights from 0.8691 to 1.3153 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of B27.19?
Under the General Equivalence Mappings, cytomegaloviral mononucleosis with other complication converts to ICD-9-CM 075 (infectious mononucleosis). The mapping is approximate, so confirm the match fits the documentation.
