2027 ICD-10-CM Diagnosis Code B27.09Gammaherpesviral mononucleosis with other complications
ICD-10-CM Codes›A00–B99›B25-B34›B27
- Billable — Valid for Submission
- Not Chronic
B27.09 is a billable ICD-10-CM diagnosis code for gammaherpesviral mononucleosis with other complications. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 865 through 866. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Viral infection.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Diffuse large B-cell lymphoma co-occurrent with chronic inflammation caused by Epstein-Barr virus
- Epstein Barr virus infection of the central nervous system
- Epstein-Barr dacryoadenitis
- Epstein-Barr virus associated gastric carcinoma
- Epstein-Barr virus encephalitis
- Epstein-Barr virus infection of the retina
- Epstein-Barr virus infectious mononucleosis
- Hepatomegaly due to gammaherpesviral mononucleosis
- Infection of lacrimal gland caused by virus
- Mucocutaneous ulcer caused by Epstein-Barr virus
- Myelitis caused by Epstein-Barr virus
- Myelitis caused by herpes virus
- Neoplastic sequelae of disorders
- Primary carcinoma of stomach due to Epstein-Barr virus disease
- Viral pneumonia due to Epstein-Barr virus infectious mononucleosis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to B27.09: its own notes plus those printed at B27 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- glandular fever
- monocytic angina
- Pfeiffer's disease
- diseases generally recognized as communicable or transmissible
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Hepatomegaly in gammaherpesviral mononucleosis
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify resistance to antimicrobial drugs (Z16.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name B27.09, its category, or a range that includes it.
Applicable To 1
These notes mention B27.09.
- O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
Excludes1 4
These codes carry an Excludes1 note naming B27.09: they are not reported together with it, unless the two conditions are unrelated.
- D72.821 Monocytosis (symptomatic)infectious mononucleosis (B27.-) names B27.-, which includes this code
- G02 Meningitis in other infectious and parasitic diseases classified elsewhereinfectious mononucleosis complicated by meningitis (B27.- with fifth character 2) names B27.-, which includes this code
- J02.8 Acute pharyngitis due to other specified organismsacute pharyngitis due to infectious mononucleosis (B27.-) names B27.-, which includes this code
- G63 Polyneuropathy in diseases classified elsewhere
Excludes2 3
These codes carry an Excludes2 note naming B27.09: its condition is not part of those codes, and both may be reported when the patient has both.
- B00 Herpesviral [herpes simplex] infectionsgammaherpesviral mononucleosis (B27.0-) names B27.0-, which includes this code
- B10 Other human herpesvirusesEpstein-Barr virus (B27.0-) names B27.0-, which includes this code
- B10 Other human herpesviruseshuman herpesvirus 4 (B27.0-) names B27.0-, which includes this code
Code First 1
These codes say to code first a condition named in the note, and B27.09 is one of the conditions named.
- K77 Liver disorders in diseases classified elsewhere
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Adenitis See Also: Lymphadenitis;
epidemic, acute B27.09
Hepatomegaly See Also: Hypertrophy, liver;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Infectious Mononucleosis
a common, acute infection usually caused by the epstein-barr virus (herpesvirus 4, human). there is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis.
Patient EducationClinical
Infectious Mononucleosis
Infectious mononucleosis (mono) is a disease caused by viruses.The most common cause is the Epstein-Barr virus (EBV). Mono is contagious, which means it can spread from person to person. It is common among teenagers and young adults, especially college students.
The full article covers:
- What is infectious mononucleosis (mono)?
- What causes infectious mononucleosis (mono)?
- What are the symptoms of infectious mononucleosis (mono)?
- How is infectious mononucleosis (mono) diagnosed?
- What are the treatments for infectious mononucleosis (mono)?
- Can infectious mononucleosis (mono) be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert B27.09 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About B27.09Overview
What is the ICD-10 code for gammaherpesviral mononucleosis with other complications?
The ICD-10-CM code for gammaherpesviral mononucleosis with other complications is B27.09 (sometimes written as B2709). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is B27.09 (Gammaherpesviral mononucleosis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report gammaherpesviral mononucleosis with other complications on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does B27.09 group to?
When gammaherpesviral mononucleosis with other complications is the principal diagnosis on an inpatient stay, it groups to MS-DRG 866, 865, with relative weights from 0.8691 to 1.3153 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of B27.09?
Under the General Equivalence Mappings, gammaherpesviral mononucleosis with other complications converts to ICD-9-CM 075 (infectious mononucleosis). The mapping is approximate, so confirm the match fits the documentation.
