2026 ICD-10-CM Diagnosis Code B25.8Other cytomegaloviral diseases

ICD-10-CM Codes›A00–B99›B25-B34›B25

ICD-10-CM B25.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B25.8 is a billable ICD-10-CM diagnosis code for other cytomegaloviral diseases. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 865 through 866, 974 through 976. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Viral infection.

Code Identity

ICD-10-CM Code
B25.8
Billable Status
Yes — Valid for Submission
Code Describes
Other cytomegaloviral diseases
Short Description
Other cytomegaloviral diseases
Same as the full description in the CMS dataset.
Parent Code
B25
Cytomegaloviral disease

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB25-B34Other viral diseases
CategoryB25Cytomegaloviral disease
This CodeB25.8Other cytomegaloviral diseases

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute gastric ulcer caused by Cytomegalovirus
  • Chorioretinitis of bilateral eyes caused by Cytomegalovirus humanbeta5
  • Chorioretinitis of left eye caused by Cytomegalovirus humanbeta5
  • Chorioretinitis of right eye caused by Cytomegalovirus humanbeta5
  • Cytomegaloviral colitis
  • Cytomegaloviral dacryoadenitis
  • Cytomegaloviral enteritis
  • Cytomegaloviral gastritis
  • Cytomegaloviral polyneuropathy
  • Cytomegaloviral retinitis
  • Cytomegalovirus chorioretinitis
  • Cytomegalovirus encephalitis
  • Cytomegalovirus infection of skin
  • Cytomegalovirus-induced glomerulonephritis
  • Duodenitis caused by Cytomegalovirus
  • Endocochlear cytomegalovirus infection
  • Esophagitis caused by Cytomegalovirus
  • Gastric ulcer caused by cytomegalovirus
  • Gastric ulcer caused by virus
  • Infection involving inner ear
  • Infection of central nervous system caused by Cytomegalovirus
  • Infection of intestine caused by Human cytomegalovirus 5
  • Infection of lacrimal gland caused by virus
  • Meningitis caused by Human cytomegalovirus 5
  • Retinitis of bilateral eyes caused by cytomegalovirus
  • Retinitis of left eye caused by cytomegalovirus
  • Retinitis of right eye caused by cytomegalovirus
  • Ulcerative cytomegalovirus lesion
  • Viral colitis
  • Viral duodenitis
  • Viral esophagitis
  • Viral kidney infection
  • Viral labyrinthitis
  • Viral posterior uveitis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Cytomegaloviral encephalitis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • cytomegaloviral
        • specified NEC
    • Encephalitis(chronic) (hemorrhagic) (idiopathic) (nonepidemic) (spurious) (subacute)
      • in (due to)
        • cytomegalovirus

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF008
Viral infection
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Viral Esophagitis

    viral infection of the esophagus. it often occurs in immunocompromised patients and it is caused by cytomegalovirus or herpes simplex virus. symptoms include pain on swallowing, fever, and retrosternal burning.

Patient EducationClinical

Cytomegalovirus Infections

Cytomegalovirus (CMV) is a virus found around the world. It is related to the viruses that cause chickenpox and infectious mononucleosis (mono). Between 50% and 80% of adults in the United States have had a CMV infection by age 40. Once CMV is in a person's body, it stays there for life.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B25.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
078.5 Cytomegaloviral disease
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B25.8Overview

Is B25.8 (Cytomegaloviral disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other cytomegaloviral diseases on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B25.8 group to?

When other cytomegaloviral diseases is the principal diagnosis on an inpatient stay, it groups to MS-DRG 865, 866, 974, 975, 976, with relative weights from 0.8696 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of B25.8?

Under the General Equivalence Mappings, other cytomegaloviral diseases converts to ICD-9-CM 078.5 (cytomegaloviral disease). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.