2027 ICD-10-CM Diagnosis Code B00.7Disseminated herpesviral disease

ICD-10-CM Codes›A00–B99›B00-B09›B00

ICD-10-CM B00.7
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

B00.7 is a billable ICD-10-CM diagnosis code for disseminated herpesviral disease. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793, 870 through 872, 974 through 976. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 41 closely related codes. Coders also document this condition as disseminated cutaneous herpes simplex infection. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Viral infection.

For Medicare Advantage risk adjustment, B00.7 maps to CMS-HCC Category 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock) under the V28 model, adding a risk factor of about 0.500 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
B00.7
Billable Status
Yes — Valid for Submission
Code Describes
Disseminated herpesviral disease
Short Description
Disseminated herpesviral disease
Same as the full description in the CMS dataset.
Parent Code
Herpesviral [herpes simplex] infections

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB00-B09Viral infections characterized by skin and mucous membrane lesions
CategoryB00Herpesviral [herpes simplex] infections
This CodeB00.7Disseminated herpesviral disease

Medicare Risk Adjustment (HCC)Billing

B00.7 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 2— Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock
Payment HCC · PY 2027 one of 52 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.500
community, non-dual, aged · ranges 0.447–0.780 across segments
Hierarchy
Top of its hierarchy
HCC 2 is not superseded by any other condition category
Prior Model (CMS-HCC V24)
HCC 2
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 2 · ESRD (V21): HCC 2 · ESRD (V24): HCC 2
ESRD V21 weights: 0.081 dialysis, 0.274–0.428 functioning graft · ESRD V24 weights: 0.087 dialysis, 0.270–0.532 functioning graft
Part D (RxHCC)
Not mapped
B00.7 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Disseminated cutaneous herpes simplex infection
  • Disseminated cutaneous infection caused by Herpes simplex co-occurrent and due to skin disease
  • Disseminated herpes simplex
  • Sepsis caused by virus
  • Sepsis due to herpes simplex
  • Visceral herpes simplex

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to B00.7: its own notes plus those printed at B00 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Herpesviral sepsis

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From B00 Herpesviral [herpes simplex] infections applies to 15 codes
  • congenital herpesviral infections (P35.2)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From B00 Herpesviral [herpes simplex] infections applies to 15 codes
  • anogenital herpesviral infection (A60.-)
  • gammaherpesviral mononucleosis (B27.0-)
  • herpangina (B08.5)
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name B00.7, its category, or a range that includes it.

Excludes2 4

These codes carry an Excludes2 note naming B00.7: its condition is not part of those codes, and both may be reported when the patient has both.

  • A41 Other sepsis
    sepsis (due to) (in) herpesviral (B00.7)
  • B10 Other human herpesviruses
    herpes simplex (B00.-) names B00.-, which includes this code
  • B10 Other human herpesviruses
    human herpesvirus NOS (B00.-) names B00.-, which includes this code
  • B10 Other human herpesviruses
    human herpesvirus 1 and 2 (B00.-) names B00.-, which includes this code

Code Also 1

These codes say B00.7 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
    herpes virus infections (B00.-) names B00.-, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF008
Viral infection
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Herpes Simplex

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted infection (STI). It affects the genitals, buttocks or anal area.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B00.7 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
054.5 Herpetic septicemia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About B00.7Overview

What is the ICD-10 code for disseminated herpesviral disease?

The ICD-10-CM code for disseminated herpesviral disease is B00.7 (sometimes written as B007). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is B00.7 (Herpesviral [herpes simplex] infections) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report disseminated herpesviral disease on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does B00.7 group to?

When disseminated herpesviral disease is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 974, 976, 872, 975, 871, 870, with relative weights from 0.7879 to 6.9432 depending on complications. Higher weights mean higher Medicare reimbursement.

Is B00.7 a CC or MCC?

CMS lists B00.7 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 41 closely related codes in its exclusion list.

Can B00.7 be reported with P35.2?

Not as a rule. The Excludes1 note at B00, which applies to B00.7, lists "congenital herpesviral infections (P35.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is B00.7?

B00.7 (disseminated herpesviral disease) maps to CMS-HCC Category 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock), commonly written as HCC 2, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 2 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does B00.7 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, B00.7 adds a risk adjustment factor of about 0.500 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.447 to 0.780 depending on the payment segment). HCC 2 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 2 category page.