2027 ICD-10-CM Diagnosis Code B00.51Herpesviral iridocyclitis

ICD-10-CM Codes›A00–B99›B00-B09›B00

ICD-10-CM B00.51
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

B00.51 is a billable ICD-10-CM diagnosis code for herpesviral iridocyclitis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 124 through 125, 791, 793, 974 through 976. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 10 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified eye disorders and Viral infection.

Code Identity

ICD-10-CM Code
B00.51
Billable Status
Yes — Valid for Submission
Code Describes
Herpesviral iridocyclitis
Short Description
Herpesviral iridocyclitis
Same as the full description in the CMS dataset.
Parent Code
Herpesviral ocular disease

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB00-B09Viral infections characterized by skin and mucous membrane lesions
CategoryB00Herpesviral [herpes simplex] infections
This CodeB00.51Herpesviral iridocyclitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral herpes simplex iridocyclitis
  • Bilateral iritis of eyes caused by Human alphaherpesvirus
  • Herpes simplex iridocyclitis
  • Herpes simplex iritis
  • Herpes simplex keratouveitis
  • Herpes simplex type 1 infection
  • Herpetic iridocyclitis
  • Iridocyclitis of bilateral eyes
  • Iridocyclitis of left eye caused by human herpes simplex virus
  • Iridocyclitis of right eye caused by human herpes simplex virus
  • Iritis of left eye caused by herpes simplex virus
  • Iritis of right eye caused by herpes simplex virus
  • Keratouveitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to B00.51: its own notes plus those printed at B00 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Herpesviral iritis
  • Herpesviral uveitis, anterior

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From B00 Herpesviral [herpes simplex] infections applies to 15 codes
  • congenital herpesviral infections (P35.2)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From B00 Herpesviral [herpes simplex] infections applies to 15 codes
  • anogenital herpesviral infection (A60.-)
  • gammaherpesviral mononucleosis (B27.0-)
  • herpangina (B08.5)
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name B00.51, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming B00.51: they are not reported together with it, unless the two conditions are unrelated.

  • H20.0 Acute and subacute iridocyclitis
    iridocyclitis, iritis, uveitis (due to) (in) herpes (simplex) (B00.51)
  • B30 Viral conjunctivitis
    herpesviral [herpes simplex] ocular disease (B00.5) names B00.5, which includes this code

Excludes2 3

These codes carry an Excludes2 note naming B00.51: its condition is not part of those codes, and both may be reported when the patient has both.

  • B10 Other human herpesviruses
    herpes simplex (B00.-) names B00.-, which includes this code
  • B10 Other human herpesviruses
    human herpesvirus NOS (B00.-) names B00.-, which includes this code
  • B10 Other human herpesviruses
    human herpesvirus 1 and 2 (B00.-) names B00.-, which includes this code

Code Also 1

These codes say B00.51 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
    herpes virus infections (B00.-) names B00.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EYE012
Other specified eye disorders
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INF008
Viral infection
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Herpes Simplex

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted infection (STI). It affects the genitals, buttocks or anal area.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B00.51 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
054.44 H simplex iridocyclitis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About B00.51Overview

What is the ICD-10 code for herpesviral iridocyclitis?

The ICD-10-CM code for herpesviral iridocyclitis is B00.51 (sometimes written as B0051). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is B00.51 (Herpesviral ocular disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report herpesviral iridocyclitis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does B00.51 group to?

When herpesviral iridocyclitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 974, 125, 976, 975, 124, with relative weights from 0.7699 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is B00.51 a CC or MCC?

CMS lists B00.51 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 10 closely related codes in its exclusion list.

Can B00.51 be reported with P35.2?

Not as a rule. The Excludes1 note at B00, which applies to B00.51, lists "congenital herpesviral infections (P35.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).