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  6. 2026 ICD-10-CM Code D71.1

2026 ICD-10-CM Diagnosis Code D71.1

Leukocyte adhesion deficiency

ICD-10-CM Code:
D71.1
ICD-10 Code for:
Leukocyte adhesion deficiency
Is Billable?
Yes - Valid for Submission
Code Navigator:

D71.1 is a billable diagnosis code used to specify a medical diagnosis of leukocyte adhesion deficiency. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    D50–D89
    • Other disorders of blood and blood-forming organs
      D70-D77
      • Functional disorders of polymorphonuclear neutrophils
        D71

Clinical Information

  • Leukocyte Adhesion Deficiency

    a rare autosomal recessive immunodeficiency disorder caused by deficiency of cd18 expression. it is characterized by defects in neutrophil adhesion and bacterial infections.

  • Leukocyte Adhesion Deficiency Type 1|LAD-1|LAD-1 Deficiency|LAD-Type I|LAD1|LFA-I Deficiency|LFA1 Immunodeficiency

    a rare immunodeficiency with an autosomal recessive pattern of inheritance. it is caused by mutation in the itgb2 gene on chromosome 21 which codes for the beta subunit of beta-2 integrin (cd18). the mutation results in significantly reduced or absent expression of cd18 on the surface of leukocytes which impairs their ability to migrate and interact with antigens. initial clinical signs include omphalitis and delayed separation of the umbilical cord. the clinical course is marked by recurrent bacterial and fungal infection without pus formation. in instances where there is < 1% expression of cd18, prognosis is dismal with a high likelihood for life-threatening infection within the first year of life.

  • Leukocyte Adhesion Deficiency Type 2|CDGIIc|Congenital Disorder of Glycosylation Type IIc|LAD-Type II|Sialyl-Lewis X Defect

    leukocyte adhesion deficiency, type ii. an inherited disease affecting the metabolism of fucose, which affects the expression of the sialyl lewis x antigen, the fucose-containing ligand for e- and p-selectins, resulting in a deficiency in neutrophil adhesion. syn sialyl-lewis x defect.

  • Leukocyte Adhesion Deficiency Type 3|LAD-3|LAD-III

    an autosomal recessive condition caused by mutation(s) in the fermt3 gene, encoding fermitin family homolog 3. it is characterized by a defect in activation of all beta integrins. it manifests clinically as severe infections with marked leukocytosis, accompanied by life-threatening bleeding episodes.

New 2026 ICD-10-CM Code

D71.1 is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • LAD-I
  • LAD-II
  • LAD-III
  • Leukocyte adhesion deficiency type I
  • Leukocyte adhesion deficiency type II
  • Leukocyte adhesion deficiency type III

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Index of External Cause of Injuries

References found for this diagnosis code in the External Cause of Injuries Index:

    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
        • type I
    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
        • type II
    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
        • type III
    • LAD(leukocyte adhesion deficiency) (LAD-I) (LAD-II) (LAD-III)

Replacement Code

D711 replaces the following previously assigned ICD-10-CM code(s):

  • D71 - Functional disorders of polymorphonuclear neutrophils

Code History

  • FY 2026 - Code Added, effective from 10/1/2025 through 9/30/2026