2026 ICD-10-CM Diagnosis Code D64.0
Hereditary sideroblastic anemia
- ICD-10-CM Code:
- D64.0
- ICD-10 Code for:
- Hereditary sideroblastic anemia
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Chronic
- Code Navigator:
D64.0 is a billable diagnosis code used to specify a medical diagnosis of hereditary sideroblastic anemia. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.
Approximate Synonyms
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Adult-onset autosomal recessive sideroblastic anemia
- Autosomal dominant sideroblastic anemia
- Autosomal recessive sideroblastic anemia
- Congenital sideroblastic anemia, B-cell immunodeficiency, periodic fever, developmental delay syndrome
- Mitochondrial myopathy with sideroblastic anemia syndrome
- Severe congenital hypochromic anemia with ringed sideroblasts
- X chromosome-linked sideroblastic anemia
- X chromosome-linked sideroblastic anemia
- X-linked sideroblastic anemia with spinocerebellar ataxia
Clinical Classification
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
Aplastic anemia
CCSR Code: BLD003
Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Clinical Information
Hereditary Sideroblastic Anemia
an inherited form of sideroblastic anemia.
Tabular List of Diseases and Injuries
The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Sex-linked hypochromic sideroblastic anemia
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) - D64.9
- hypochromic (idiopathic) (microcytic) (normoblastic) - D50.9
- familial sex-linked - D64.0
- sideroblastic, sex-linked - D64.0
- sideroblastic - D64.3
- hereditary - D64.0
- hypochromic, sex-linked - D64.0
Index of External Cause of Injuries
References found for this diagnosis code in the External Cause of Injuries Index:
- Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- hypochromic (idiopathic) (microcytic) (normoblastic)
- familial sex-linked
- Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- hypochromic (idiopathic) (microcytic) (normoblastic)
- sideroblastic, sex-linked
- Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- sideroblastic
- hereditary
- Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- sideroblastic
- hypochromic, sex-linked
Convert D64.0 to ICD-9-CM
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
Sideroblastic anemia
ICD-9-CM: 285.0
Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.
Patient Education
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.
Conditions that may lead to anemia include:
- Heavy periods
- Pregnancy
- Ulcers
- Colon polyps or colon cancer
- Inherited disorders
- A diet that does not have enough iron, folic acid or vitamin B12
- Blood disorders such as sickle cell anemia and thalassemia, or cancer
- Aplastic anemia, a condition that can be inherited or acquired
- G6PD deficiency, a metabolic disorder
Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.
Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.
NIH: National Heart, Lung, and Blood Institute
[Learn More in MedlinePlus]
X-linked sideroblastic anemia
X-linked sideroblastic anemia belongs to a group of disorders that are characterized by a shortage of healthy red blood cells (anemia). X-linked sideroblastic anemia prevents developing red blood cells from making enough hemoglobin, which is the protein that carries oxygen in the blood. People with X-linked sideroblastic anemia have red blood cells that are smaller than normal (microcytic) and appear pale (hypochromic) because of the shortage of hemoglobin. This disorder also leads to an abnormal accumulation of iron in red blood cells. The iron-loaded red blood cells, which are present in bone marrow, are called ring sideroblasts.
The signs and symptoms of X-linked sideroblastic anemia are caused by a combination of too little hemoglobin and too much iron. Common signs and symptoms include extreme tiredness (fatigue), dizziness, a rapid heartbeat, pale skin, and an enlarged liver and spleen (hepatosplenomegaly). Over time, severe health problems such as heart disease and liver damage (cirrhosis), can result from the buildup of iron in these organs.
Males with X-linked sideroblastic anemia typically have the classic signs and symptoms of the condition, while females tend to be less severely affected. Females with X-linked sideroblastic anemia usually develop features of the condition in mid to late adulthood, while affected males often first experience symptoms in adolescence to early adulthood.
[Learn More in MedlinePlus]
X-linked sideroblastic anemia and ataxia
X-linked sideroblastic anemia and ataxia is a rare condition characterized by a blood disorder called sideroblastic anemia and movement problems known as ataxia. This condition occurs only in males.
Sideroblastic anemia results when developing red blood cells called erythroblasts do not make enough hemoglobin, which is the protein that carries oxygen in the blood. People with X-linked sideroblastic anemia and ataxia have mature red blood cells that are smaller than normal (microcytic) and appear pale (hypochromic) because of the shortage of hemoglobin. This disorder also leads to an abnormal accumulation of iron in red blood cells. The iron-loaded erythroblasts, which are present in bone marrow, are called ring sideroblasts. These abnormal cells give the condition its name. Unlike other forms of sideroblastic anemia, X-linked sideroblastic anemia and ataxia does not cause a potentially dangerous buildup of iron in the body. The anemia is typically mild and usually does not cause any symptoms.
X-linked sideroblastic anemia and ataxia causes problems with balance and coordination that appear early in life. The ataxia primarily affects the trunk, making it difficult to sit, stand, and walk unassisted. In addition to ataxia, people with this condition often have trouble coordinating movements that involve judging distance or scale (dysmetria) and find it difficult to make rapid, alternating movements (dysdiadochokinesis). Mild speech difficulties (dysarthria), tremor, and abnormal eye movements have also been reported in some affected individuals.
[Learn More in MedlinePlus]
Code History
- FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026
- FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.