2027 ICD-10-CM Diagnosis Code P78.3Noninfective neonatal diarrhea

ICD-10-CM Codes›P00–P96›P76-P78›P78

ICD-10-CM P78.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P78.3 is a billable ICD-10-CM diagnosis code for noninfective neonatal diarrhea. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 794. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neonatal digestive and feeding disorders.

Code Identity

ICD-10-CM Code
P78.3
Billable Status
Yes — Valid for Submission
Code Describes
Noninfective neonatal diarrhea
Short Description
Noninfective neonatal diarrhea
Same as the full description in the CMS dataset.
Parent Code
Other perinatal digestive system disorders

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP76-P78Digestive system disorders of newborn
CategoryP78Other perinatal digestive system disorders
This CodeP78.3Noninfective neonatal diarrhea

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute diarrhea
  • Congenital secretory diarrhea
  • Diarrhea
  • Diarrhea and vomiting
  • Diarrhea symptom
  • Diarrheal disorder
  • Digestive symptom
  • Hemorrhagic diarrhea
  • Hypokalemic alkalosis
  • Hypokalemic alkalosis due to diarrhea
  • Infantile erythroderma, failure to thrive and diarrhea syndrome
  • Inflammatory diarrhea
  • Neonatal diarrhea
  • Non-infective diarrhea
  • Non-infective neonatal diarrhea
  • Protracted diarrhea
  • Secretory diarrhea
  • Severe diarrhea

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P78.3: its own notes plus those printed at P78 and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Neonatal diarrhea NOS

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From P78 Other perinatal digestive system disorders applies to 10 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P78.3, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming P78.3: they are not reported together with it, unless the two conditions are unrelated.

  • K52.9 Noninfective gastroenteritis and colitis, unspecified
    neonatal diarrhea (noninfective) (P78.3)
  • R19.7 Diarrhea, unspecified
    neonatal diarrhea (P78.3)

Excludes2 1

These codes carry an Excludes2 note naming P78.3: its condition is not part of those codes, and both may be reported when the patient has both.

  • P37 Other congenital infectious and parasitic diseases
    noninfectious neonatal diarrhea (P78.3)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL012
Neonatal digestive and feeding disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Diarrhea

Diarrhea is loose, watery stools (bowel movements). You have diarrhea if you have loose stools three or more times in one day. Acute diarrhea is diarrhea that lasts a short time. It is a common problem. It usually lasts about one or two days, but it may last longer. Then it goes away on its own.

The full article covers:

  • What is diarrhea?
  • What causes diarrhea?
  • Who is at risk for diarrhea?
  • What other symptoms might I have with diarrhea?
  • When do I need to see a health care provider for diarrhea?
  • How is the cause of diarrhea diagnosed?
  • What are the treatments for diarrhea?
  • Can diarrhea be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P78.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
777.8 Perinat GI sys dis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P78.3Overview

What is the ICD-10 code for noninfective neonatal diarrhea?

The ICD-10-CM code for noninfective neonatal diarrhea is P78.3 (sometimes written as P783). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P78.3 (Other perinatal digestive system disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report noninfective neonatal diarrhea on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P78.3 group to?

When noninfective neonatal diarrhea is the principal diagnosis on an inpatient stay, it groups to MS-DRG 794 (neonate with Other Significant Problems), which carries a relative weight of 1.4934. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of P78.3?

Under the General Equivalence Mappings, noninfective neonatal diarrhea converts to ICD-9-CM 777.8 (perinat GI sys dis NEC). The mapping is approximate, so confirm the match fits the documentation.