2026 ICD-10-CM Diagnosis Code K27.1Acute peptic ulcer, site unspecified, with perforation

ICD-10-CM Codes›K00–K95›K20-K31›K27

ICD-10-CM K27.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K27.1 is a billable ICD-10-CM diagnosis code for acute peptic ulcer, site unspecified, with perforation. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 380 through 382. Coders also document this condition as acute peptic ulcer with perforation. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Gastroduodenal ulcer and Gastrointestinal and biliary perforation.

Code Identity

ICD-10-CM Code
K27.1
Billable Status
Yes — Valid for Submission
Code Describes
Acute peptic ulcer, site unspecified, with perforation
Short Description
Acute peptic ulcer, site unspecified, with perforation
Same as the full description in the CMS dataset.
Parent Code
K27
Peptic ulcer, site unspecified

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK20-K31Diseases of esophagus, stomach and duodenum
CategoryK27Peptic ulcer, site unspecified
This CodeK27.1Acute peptic ulcer, site unspecified, with perforation

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute peptic ulcer with perforation
  • Acute peptic ulcer with perforation AND obstruction
  • Acute peptic ulcer with perforation but without obstruction

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Ulcer, ulcerated, ulcerating, ulceration, ulcerative
      • peptic (site unspecified)
        • acute
          • with
            • perforation

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG005
Gastroduodenal ulcer
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR DIG006
Gastrointestinal and biliary perforation
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Peptic Ulcer

A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. A burning stomach pain is the most common symptom. The pain:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K27.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
533.10 Ac peptic ulcer w perfor
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K27.1Overview

Is K27.1 (Peptic ulcer, site unspecified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report acute peptic ulcer, site unspecified, with perforation on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K27.1 group to?

When acute peptic ulcer, site unspecified, with perforation is the principal diagnosis on an inpatient stay, it groups to MS-DRG 380, 381, 382, with relative weights from 0.8006 to 1.9622 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of K27.1?

Under the General Equivalence Mappings, acute peptic ulcer, site unspecified, with perforation converts to ICD-9-CM 533.10 (ac peptic ulcer w perfor). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.