2026 ICD-10-CM Diagnosis Code I42.3Endomyocardial (eosinophilic) disease

ICD-10-CM Codes›I00–I99›I30-I5A›I42

ICD-10-CM I42.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I42.3 is a billable ICD-10-CM diagnosis code for endomyocardial (eosinophilic) disease. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 314 through 316. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Myocarditis and cardiomyopathy.

Code Identity

ICD-10-CM Code
I42.3
Billable Status
Yes — Valid for Submission
Code Describes
Endomyocardial (eosinophilic) disease
Short Description
Endomyocardial (eosinophilic) disease
Same as the full description in the CMS dataset.
Parent Code
I42
Cardiomyopathy

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI30-I5AOther forms of heart disease
CategoryI42Cardiomyopathy
This CodeI42.3Endomyocardial (eosinophilic) disease

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Endomyocardial disease
  • Endomyocardial fibrosis
  • Primary endomyocardial fibrosis cardiomyopathy
  • Primary endomyocardial fibrosis restrictive cardiomyopathy
  • Primary eosinophilic endomyocardial cardiomyopathy
  • Primary eosinophilic endomyocardial restrictive cardiomyopathy
  • Primary restrictive cardiomyopathy
  • Restrictive cardiomyopathy with endomyocardial fibrosis
  • Tropical endomyocardial fibrosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Endomyocardial (tropical) fibrosis
  • Löffler's endocarditis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Becker's
      • disease
        • idiopathic mural endomyocardial disease
    • Disease, diseased
      • Becker
        • idiopathic mural endomyocardial
    • Disease, diseased
      • endomyocardial (eosinophilic)
    • Endocarditis(chronic) (marantic) (nonbacterial) (thrombotic) (valvular)
      • Löffler's
    • Endomyocardiopathy, South African
    • Endomyofibrosis
    • Fibrosis, fibrotic
      • endomyocardial (tropical)
    • Löffler's
      • endocarditis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR005
Myocarditis and cardiomyopathy
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Endomyocardial Fibrosis

    a condition characterized by the thickening of the ventricular endocardium and subendocardium (myocardium), seen mostly in children and young adults in the tropical climate. the fibrous tissue extends from the apex toward and often involves the heart valves causing restrictive blood flow into the respective ventricles (cardiomyopathy, restrictive).

  • Endomyocardial Fibrosis

    a disease characterized by fibrotic thickening of the endocardium, particularly the right and/or left inflow tracts. the disease often involves the atrioventricular valves, leading to valvular regurgitaion. it most commonly occurs in children living within 15 degrees of the equator.

Patient EducationClinical

Cardiomyopathy

Cardiomyopathy is the name for diseases of the heart muscle. These diseases enlarge your heart muscle or make it thicker and more rigid than normal. In rare cases, scar tissue replaces the muscle tissue.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I42.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
425.0 Endomyocardial fibrosis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I42.3Overview

Is I42.3 (Cardiomyopathy) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report endomyocardial (eosinophilic) disease on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I42.3 group to?

When endomyocardial (eosinophilic) disease is the principal diagnosis on an inpatient stay, it groups to MS-DRG 314, 315, 316, with relative weights from 0.6821 to 2.0852 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of I42.3?

Under the General Equivalence Mappings, endomyocardial (eosinophilic) disease converts to ICD-9-CM 425.0 (endomyocardial fibrosis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.