2027 ICD-10-CM Diagnosis Code H46.8Other optic neuritis
ICD-10-CM Codes›H00–H59›H46-H47›H46
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Chronic Condition
H46.8 is a billable ICD-10-CM diagnosis code for other optic neuritis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 123. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 12 closely related codes. Coders also document this condition as autoimmune optic neuropathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neuro-ophthalmology.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Autoimmune optic neuropathy
- Disorder of cranial nerve caused by ionizing radiation
- Disorder of optic nerve caused by radiation
- Infiltrative optic neuropathy
- Inherited optic neuropathy
- Neuropathy caused by ionizing radiation
- Optic neuropathy due to and following radiotherapy
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to H46.8: its own notes plus those printed at H46 and Chapter 7. A note printed at a category, block or chapter applies to every code under it.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury (trauma) of eye and orbit (S05.-)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- syphilis related eye disorders (A50.01, A50.3-, A51.43, A52.71)
Notes
General instructions on how these codes are used.
- Use an external cause code following the code for the eye condition, if applicable, to identify the cause of the eye condition
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name H46.8, its category, or a range that includes it.
Excludes2 2
These codes carry an Excludes2 note naming H46.8: its condition is not part of those codes, and both may be reported when the patient has both.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Optic Neuritis
inflammation of the optic nerve. commonly associated conditions include autoimmune disorders such as multiple sclerosis, infections, and granulomatous diseases. clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (marcus-gunn pupil), and in some instances optic disc hyperemia and swelling. inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
Patient EducationClinical
Optic Nerve Disorders
The optic nerve is a bundle of more than 1 million nerve fibers that carry visual messages. You have one connecting the back of each eye (your retina) to your brain. Damage to an optic nerve can cause vision loss. The type of vision loss and how severe it is depends on where the damage occurs. It may affect one or both eyes.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert H46.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About H46.8Overview
What is the ICD-10 code for other optic neuritis?
The ICD-10-CM code for other optic neuritis is H46.8 (sometimes written as H468). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is H46.8 (Optic neuritis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other optic neuritis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does H46.8 group to?
When other optic neuritis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 123 (neurological Eye Disorders), which carries a relative weight of 0.8218. Higher weights mean higher Medicare reimbursement.
Is H46.8 a CC or MCC?
CMS lists H46.8 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 12 closely related codes in its exclusion list.
What is the ICD-9 equivalent of H46.8?
Under the General Equivalence Mappings, other optic neuritis converts to ICD-9-CM 377.39 (optic neuritis NEC). The mapping is a direct match.
