2027 ICD-10-CM Diagnosis Code F17.221Nicotine dependence, chewing tobacco, in remission

ICD-10-CM Codes›F01–F99›F10-F19›F17

ICD-10-CM F17.221
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

F17.221 is a billable ICD-10-CM diagnosis code for nicotine dependence, chewing tobacco, in remission. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor. Coders also document this condition as nicotine dependence in remission. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Mental and substance use disorders in remission.

Code Identity

ICD-10-CM Code
F17.221
Billable Status
Yes — Valid for Submission
Code Describes
Nicotine dependence, chewing tobacco, in remission
Short Description
Nicotine dependence, chewing tobacco, in remission
Same as the full description in the CMS dataset.
Parent Code
F17.22
Nicotine dependence, chewing tobacco

Code Classification

ChapterF01–F99Mental and behavioural disorders
SectionF10-F19Mental and behavioral disorders due to psychoactive substance use
CategoryF17Nicotine dependence
This CodeF17.221Nicotine dependence, chewing tobacco, in remission

Code EditsBilling

Medicare Code Editor checks that affect claim validity for F17.221.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Nicotine dependence in remission
  • Tobacco dependence caused by chewing tobacco
  • Tobacco dependence caused by chewing tobacco in remission
  • Tobacco dependence in remission

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to F17.221: its own notes plus those printed at F17 and Chapter 5. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • disorders of psychological development

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Tobacco use disorder, chewing tobacco, mild, in early remission
  • Tobacco use disorder, chewing tobacco, mild, in sustained remission
  • Tobacco use disorder, chewing tobacco, moderate, in early remission
  • Tobacco use disorder, chewing tobacco, moderate, in sustained remission
  • Tobacco use disorder, chewing tobacco, severe, in early remission
  • Tobacco use disorder, chewing tobacco, severe, in sustained remission

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From F17 Nicotine dependence applies to 20 codes
  • history of tobacco dependence (Z87.891)
  • tobacco use NOS (Z72.0)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From F17 Nicotine dependence applies to 20 codes
  • tobacco use (smoking) during pregnancy, childbirth and the puerperium (O99.33-)
  • toxic effect of nicotine (T65.2-)
From Chapter 5 (F01-F99) Mental and behavioural disorders applies to 872 codes
  • symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name F17.221, its category, or a range that includes it.

Applicable To 1

These notes mention F17.221.

  • Z81.2 Family history of tobacco abuse and dependence
    Conditions classifiable to F17.- names F17.-, which includes this code

Excludes1 4

These codes carry an Excludes1 note naming F17.221: they are not reported together with it, unless the two conditions are unrelated.

  • Z72.0 Tobacco use
    nicotine dependence (F17.2-) names F17.2-, which includes this code
  • Z72.0 Tobacco use
    tobacco dependence (F17.2-) names F17.2-, which includes this code
  • Z77.22 Contact with and (suspected) exposure to environmental tobacco smoke (acute) (chronic)
    nicotine dependence (F17.-) names F17.-, which includes this code
  • Z87.891 Personal history of nicotine dependence
    current nicotine dependence (F17.2-) names F17.2-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming F17.221: its condition is not part of those codes, and both may be reported when the patient has both.

  • T65.2 Toxic effect of tobacco and nicotine
    nicotine dependence (F17.-) names F17.-, which includes this code

Use Additional Code 49

These codes say to use an additional code from the note, and F17.221 is one of the codes named.

  • C00 Malignant neoplasm of lip
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C01 Malignant neoplasm of base of tongue
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C02 Malignant neoplasm of other and unspecified parts of tongue
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C03 Malignant neoplasm of gum
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C04 Malignant neoplasm of floor of mouth
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C05 Malignant neoplasm of palate
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C06 Malignant neoplasm of other and unspecified parts of mouth
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C07 Malignant neoplasm of parotid gland
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C08 Malignant neoplasm of other and unspecified major salivary glands
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C09 Malignant neoplasm of tonsil
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C10 Malignant neoplasm of oropharynx
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C11 Malignant neoplasm of nasopharynx
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C12 Malignant neoplasm of pyriform sinus
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C13 Malignant neoplasm of hypopharynx
    tobacco dependence (F17.-) names F17.-, which includes this code
  • C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
    tobacco dependence (F17.-) names F17.-, which includes this code

34 more Use Additional Code notes name this code. Browse all Use Additional Code notes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD026
Mental and substance use disorders in remission
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Nicotine Dependence

    physical and psychological dependence on nicotine.

Patient EducationClinical

Smokeless Tobacco

Many people who chew tobacco or dip snuff think it's safer than smoking. But you don't have to smoke tobacco for it to be dangerous. Chewing or dipping carries risks like:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert F17.221 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
305.1 Tobacco use disorder
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About F17.221Overview

What is the ICD-10 code for nicotine dependence, chewing tobacco, in remission?

The ICD-10-CM code for nicotine dependence, chewing tobacco, in remission is F17.221 (sometimes written as F17221). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is F17.221 (Nicotine dependence, chewing tobacco) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report nicotine dependence, chewing tobacco, in remission on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does F17.221 group to?

On inpatient claims, nicotine dependence, chewing tobacco, in remission maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can F17.221 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because nicotine dependence, chewing tobacco, in remission describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Can F17.221 be reported with Z87.891?

Not as a rule. The Excludes1 note at F17, which applies to F17.221, lists "history of tobacco dependence (Z87.891)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).