Dependence (on) (syndrome) - in the ICD-10-CM Index
Annotation Back-References in the 2025 ICD-10-CM Index to Diseases and Injuries
Browse the ICD-10-CM codes with references applicable to the clinical term "dependence (on) (syndrome)"
Dependence (on) (syndrome) - F19.20 Other psychoactive substance dependence, uncomplicated
alcohol (ethyl) (methyl) (without remission) - F10.20 Alcohol dependence, uncomplicated
counseling and surveillance - Z71.41 Alcohol abuse counseling and surveillance of alcoholic
in remission - F10.21 Alcohol dependence, in remission
with
amnestic disorder, persisting - F10.26 Alcohol dependence with alcohol-induced persisting amnestic disorder
anxiety disorder - F10.280 Alcohol dependence with alcohol-induced anxiety disorder
dementia, persisting - F10.27 Alcohol dependence with alcohol-induced persisting dementia
intoxication - F10.229 Alcohol dependence with intoxication, unspecified
mood disorder - F10.24 Alcohol dependence with alcohol-induced mood disorder
psychotic disorder - F10.259 Alcohol dependence with alcohol-induced psychotic disorder, unspecified
remission - F10.21 Alcohol dependence, in remission
sexual dysfunction - F10.281 Alcohol dependence with alcohol-induced sexual dysfunction
sleep disorder - F10.282 Alcohol dependence with alcohol-induced sleep disorder
specified disorder NEC - F10.288 Alcohol dependence with other alcohol-induced disorder
withdrawal - F10.239 Alcohol dependence with withdrawal, unspecified
amobarbital - See: Dependence, drug, sedative;
amphetamine (s) (type) - See: Dependence, drug, stimulant NEC;
amytal (sodium) - See: Dependence, drug, sedative;
analgesic NEC - F55.8 Abuse of other non-psychoactive substances
anesthetic (agent) (gas) (general) (local) NEC - See: Dependence, drug, psychoactive NEC;
anxiolytic NEC - See: Dependence, drug, sedative;
barbital (s) - See: Dependence, drug, sedative;
barbiturate (s) (compounds) (drugs classifiable to T42) - See: Dependence, drug, sedative;
benzedrine - See: Dependence, drug, stimulant NEC;
bhang - See: Dependence, drug, cannabis;
bromide (s) NEC - See: Dependence, drug, sedative;
caffeine - See: Dependence, drug, stimulant NEC;
cannabis (sativa) (indica) (resin) (derivatives) (type) - See: Dependence, drug, cannabis;
chloral (betaine) (hydrate) - See: Dependence, drug, sedative;
chlordiazepoxide - See: Dependence, drug, sedative;
coca (leaf) (derivatives) - See: Dependence, drug, cocaine;
cocaine - See: Dependence, drug, cocaine;
codeine - See: Dependence, drug, opioid;
combinations of drugs - F19.20 Other psychoactive substance dependence, uncomplicated
dagga - See: Dependence, drug, cannabis;
demerol - See: Dependence, drug, opioid;
dexamphetamine - See: Dependence, drug, stimulant NEC;
dexedrine - See: Dependence, drug, stimulant NEC;
dextromethorphan - See: Dependence, drug, opioid;
dextromoramide - See: Dependence, drug, opioid;
dextro-nor-pseudo-ephedrine - See: Dependence, drug, stimulant NEC;
dextrorphan - See: Dependence, drug, opioid;
diazepam - See: Dependence, drug, sedative;
dilaudid - See: Dependence, drug, opioid;
D-lysergic acid diethylamide - See: Dependence, drug, hallucinogen;
drug NEC - F19.20 Other psychoactive substance dependence, uncomplicated
cannabis - F12.20 Cannabis dependence, uncomplicated
in remission - F12.21 Cannabis dependence, in remission
with
anxiety disorder - F12.280 Cannabis dependence with cannabis-induced anxiety disorder
intoxication - F12.229 Cannabis dependence with intoxication, unspecified
other specified disorder - F12.288 Cannabis dependence with other cannabis-induced disorder
psychosis - F12.259 Cannabis dependence with psychotic disorder, unspecified
unspecified disorder - F12.29 Cannabis dependence with unspecified cannabis-induced disorder
withdrawal - F12.23 Cannabis dependence with withdrawal
cocaine - F14.20 Cocaine dependence, uncomplicated
in remission - F14.21 Cocaine dependence, in remission
with
anxiety disorder - F14.280 Cocaine dependence with cocaine-induced anxiety disorder
intoxication - F14.229 Cocaine dependence with intoxication, unspecified
mood disorder - F14.24 Cocaine dependence with cocaine-induced mood disorder
other specified disorder - F14.288 Cocaine dependence with other cocaine-induced disorder
psychosis - F14.259 Cocaine dependence with cocaine-induced psychotic disorder, unspecified
sexual dysfunction - F14.281 Cocaine dependence with cocaine-induced sexual dysfunction
sleep disorder - F14.282 Cocaine dependence with cocaine-induced sleep disorder
unspecified disorder - F14.29 Cocaine dependence with unspecified cocaine-induced disorder
withdrawal - F14.23 Cocaine dependence with withdrawal
withdrawal symptoms in newborn - P96.1 Neonatal withdrawal symptoms from maternal use of drugs of addiction
counseling and surveillance - Z71.51 Drug abuse counseling and surveillance of drug abuser
hallucinogen - F16.20 Hallucinogen dependence, uncomplicated
in remission - F16.21 Hallucinogen dependence, in remission
with
anxiety disorder - F16.280 Hallucinogen dependence with hallucinogen-induced anxiety disorder
flashbacks - F16.283 Hallucinogen dependence with hallucinogen persisting perception disorder (flashbacks)
intoxication - F16.229 Hallucinogen dependence with intoxication, unspecified
mood disorder - F16.24 Hallucinogen dependence with hallucinogen-induced mood disorder
other specified disorder - F16.288 Hallucinogen dependence with other hallucinogen-induced disorder
perception disorder, persisting - F16.283 Hallucinogen dependence with hallucinogen persisting perception disorder (flashbacks)
psychosis - F16.259 Hallucinogen dependence with hallucinogen-induced psychotic disorder, unspecified
unspecified disorder - F16.29 Hallucinogen dependence with unspecified hallucinogen-induced disorder
in remission - F19.21 Other psychoactive substance dependence, in remission
inhalant - F18.20 Inhalant dependence, uncomplicated
in remission - F18.21 Inhalant dependence, in remission
with
anxiety disorder - F18.280 Inhalant dependence with inhalant-induced anxiety disorder
dementia, persisting - F18.27 Inhalant dependence with inhalant-induced dementia
intoxication - F18.229 Inhalant dependence with intoxication, unspecified
mood disorder - F18.24 Inhalant dependence with inhalant-induced mood disorder
other specified disorder - F18.288 Inhalant dependence with other inhalant-induced disorder
psychosis - F18.259 Inhalant dependence with inhalant-induced psychotic disorder, unspecified
unspecified disorder - F18.29 Inhalant dependence with unspecified inhalant-induced disorder
nicotine - F17.200 Nicotine dependence, unspecified, uncomplicated
chewing tobacco - F17.220 Nicotine dependence, chewing tobacco, uncomplicated
with disorder - F17.229 Nicotine dependence, chewing tobacco, with unspecified nicotine-induced disorders
cigarettes - F17.210 Nicotine dependence, cigarettes, uncomplicated
with disorder - F17.219 Nicotine dependence, cigarettes, with unspecified nicotine-induced disorders
specified product NEC - F17.290 Nicotine dependence, other tobacco product, uncomplicated
with disorder - F17.299 Nicotine dependence, other tobacco product, with unspecified nicotine-induced disorders
with disorder - F17.209 Nicotine dependence, unspecified, with unspecified nicotine-induced disorders
opioid - F11.20 Opioid dependence, uncomplicated
in remission - F11.21 Opioid dependence, in remission
with
intoxication - F11.229 Opioid dependence with intoxication, unspecified
mood disorder - F11.24 Opioid dependence with opioid-induced mood disorder
opioid-associated amnestic syndrome - F11.288 Opioid dependence with other opioid-induced disorder
other specified disorder - F11.288 Opioid dependence with other opioid-induced disorder
psychosis - F11.259 Opioid dependence with opioid-induced psychotic disorder, unspecified
sexual dysfunction - F11.281 Opioid dependence with opioid-induced sexual dysfunction
sleep disorder - F11.282 Opioid dependence with opioid-induced sleep disorder
unspecified disorder - F11.29 Opioid dependence with unspecified opioid-induced disorder
withdrawal - F11.23 Opioid dependence with withdrawal
psychoactive NEC - F19.20 Other psychoactive substance dependence, uncomplicated
in remission - F19.21 Other psychoactive substance dependence, in remission
with
amnestic disorder - F19.26 Other psychoactive substance dependence with psychoactive substance-induced persisting amnestic disorder
anxiety disorder - F19.280 Other psychoactive substance dependence with psychoactive substance-induced anxiety disorder
dementia - F19.27 Other psychoactive substance dependence with psychoactive substance-induced persisting dementia
intoxication - F19.229 Other psychoactive substance dependence with intoxication, unspecified
uncomplicated - F19.220 Other psychoactive substance dependence with intoxication, uncomplicated
with
mood disorder - F19.24 Other psychoactive substance dependence with psychoactive substance-induced mood disorder
other specified disorder - F19.288 Other psychoactive substance dependence with other psychoactive substance-induced disorder
psychosis - F19.259 Other psychoactive substance dependence with psychoactive substance-induced psychotic disorder, unspecified
sexual dysfunction - F19.281 Other psychoactive substance dependence with psychoactive substance-induced sexual dysfunction
sleep disorder - F19.282 Other psychoactive substance dependence with psychoactive substance-induced sleep disorder
unspecified disorder - F19.29 Other psychoactive substance dependence with unspecified psychoactive substance-induced disorder
withdrawal - F19.239 Other psychoactive substance dependence with withdrawal, unspecified
sedative, hypnotic or anxiolytic - F13.20 Sedative, hypnotic or anxiolytic dependence, uncomplicated
in remission - F13.21 Sedative, hypnotic or anxiolytic dependence, in remission
with
amnestic disorder - F13.26 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced persisting amnestic disorder
anxiety disorder - F13.280 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced anxiety disorder
dementia, persisting - F13.27 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced persisting dementia
intoxication - F13.229 Sedative, hypnotic or anxiolytic dependence with intoxication, unspecified
mood disorder - F13.24 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced mood disorder
other specified disorder - F13.288 Sedative, hypnotic or anxiolytic dependence with other sedative, hypnotic or anxiolytic-induced disorder
psychosis - F13.259 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder, unspecified
sexual dysfunction - F13.281 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced sexual dysfunction
sleep disorder - F13.282 Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced sleep disorder
unspecified disorder - F13.29 Sedative, hypnotic or anxiolytic dependence with unspecified sedative, hypnotic or anxiolytic-induced disorder
withdrawal - F13.239 Sedative, hypnotic or anxiolytic dependence with withdrawal, unspecified
uncomplicated - F13.230 Sedative, hypnotic or anxiolytic dependence with withdrawal, uncomplicated
with
stimulant NEC - F15.20 Other stimulant dependence, uncomplicated
in remission - F15.21 Other stimulant dependence, in remission
with
anxiety disorder - F15.280 Other stimulant dependence with stimulant-induced anxiety disorder
intoxication - F15.229 Other stimulant dependence with intoxication, unspecified
mood disorder - F15.24 Other stimulant dependence with stimulant-induced mood disorder
other specified disorder - F15.288 Other stimulant dependence with other stimulant-induced disorder
psychosis - F15.259 Other stimulant dependence with stimulant-induced psychotic disorder, unspecified
sexual dysfunction - F15.281 Other stimulant dependence with stimulant-induced sexual dysfunction
sleep disorder - F15.282 Other stimulant dependence with stimulant-induced sleep disorder
unspecified disorder - F15.29 Other stimulant dependence with unspecified stimulant-induced disorder
withdrawal - F15.23 Other stimulant dependence with withdrawal
with sleep disorder - F19.282 Other psychoactive substance dependence with psychoactive substance-induced sleep disorder
ethyl
alcohol (without remission) - F10.20 Alcohol dependence, uncomplicated
with remission - F10.21 Alcohol dependence, in remission
bromide - See: Dependence, drug, sedative;
carbamate - F19.20 Other psychoactive substance dependence, uncomplicated
chloride - F19.20 Other psychoactive substance dependence, uncomplicated
morphine - See: Dependence, drug, opioid;
ganja - See: Dependence, drug, cannabis;
glue (airplane) (sniffing) - See: Dependence, drug, inhalant;
glutethimide - See: Dependence, drug, sedative;
hallucinogenics - See: Dependence, drug, hallucinogen;
hashish - See: Dependence, drug, cannabis;
hemp - See: Dependence, drug, cannabis;
heroin (salt) (any) - See: Dependence, drug, opioid;
hypnotic NEC - See: Dependence, drug, sedative;
Indian hemp - See: Dependence, drug, cannabis;
inhalants - See: Dependence, drug, inhalant;
khat - See: Dependence, drug, stimulant NEC;
laudanum - See: Dependence, drug, opioid;
LSD (-25) (derivatives) - See: Dependence, drug, hallucinogen;
luminal - See: Dependence, drug, sedative;
lysergic acid - See: Dependence, drug, hallucinogen;
maconha - See: Dependence, drug, cannabis;
marihuana - See: Dependence, drug, cannabis;
meprobamate - See: Dependence, drug, sedative;
mescaline - See: Dependence, drug, hallucinogen;
methadone - See: Dependence, drug, opioid;
methamphetamine (s) - See: Dependence, drug, stimulant NEC;
methaqualone - See: Dependence, drug, sedative;
methyl
alcohol (without remission) - F10.20 Alcohol dependence, uncomplicated
with remission - F10.21 Alcohol dependence, in remission
bromide - See: Dependence, drug, sedative;
morphine - See: Dependence, drug, opioid;
phenidate - See: Dependence, drug, stimulant NEC;
sulfonal - See: Dependence, drug, sedative;
morphine (sulfate) (sulfite) (type) - See: Dependence, drug, opioid;
narcotic (drug) NEC - See: Dependence, drug, opioid;
nembutal - See: Dependence, drug, sedative;
neraval - See: Dependence, drug, sedative;
neravan - See: Dependence, drug, sedative;
neurobarb - See: Dependence, drug, sedative;
nicotine - See: Dependence, drug, nicotine;
nitrous oxide - F19.20 Other psychoactive substance dependence, uncomplicated
nonbarbiturate sedatives and tranquilizers with similar effect - See: Dependence, drug, sedative;
on
artificial heart (fully implantable) (mechanical) - Z95.812 Presence of fully implantable artificial heart
aspirator - Z99.0 Dependence on aspirator
care provider (because of) - Z74.9 Problem related to care provider dependency, unspecified
machine - Z99.89 Dependence on other enabling machines and devices
renal dialysis (hemodialysis) (peritoneal) - Z99.2 Dependence on renal dialysis
respirator - Z99.11 Dependence on respirator [ventilator] status
ventilator - Z99.11 Dependence on respirator [ventilator] status
wheelchair - Z99.3 Dependence on wheelchair
opiate - See: Dependence, drug, opioid;
opioids - See: Dependence, drug, opioid;
opium (alkaloids) (derivatives) (tincture) - See: Dependence, drug, opioid;
oxygen (long-term) (supplemental) - Z99.81 Dependence on supplemental oxygen
paraldehyde - See: Dependence, drug, sedative;
paregoric - See: Dependence, drug, opioid;
pentobarbital - See: Dependence, drug, sedative;
pentobarbitone (sodium) - See: Dependence, drug, sedative;
pentothal - See: Dependence, drug, sedative;
peyote - See: Dependence, drug, hallucinogen;
phenmetrazine - See: Dependence, drug, stimulant NEC;
phenobarbital - See: Dependence, drug, sedative;
polysubstance - F19.20 Other psychoactive substance dependence, uncomplicated
psilocibin, psilocin, psilocyn, psilocyline - See: Dependence, drug, hallucinogen;
psychostimulant NEC - See: Dependence, drug, stimulant NEC;
secobarbital - See: Dependence, drug, sedative;
seconal - See: Dependence, drug, sedative;
sedative NEC - See: Dependence, drug, sedative;
specified drug NEC - See: Dependence, drug;
stimulant NEC - See: Dependence, drug, stimulant NEC;
substance NEC - See: Dependence, drug;
supplemental oxygen - Z99.81 Dependence on supplemental oxygen
tobacco - See: Dependence, drug, nicotine;
counseling and surveillance - Z71.6 Tobacco abuse counseling
tranquilizer NEC - See: Dependence, drug, sedative;
vitamin B6 - E53.1 Pyridoxine deficiency
volatile solvents - See: Dependence, drug, inhalant;
with remission - F19.21 Other psychoactive substance dependence, in remission
Applicable Clinical Terms Definitions
Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Cocaine: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Codeine: An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough.
Dextromethorphan: Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Dextrorphan: Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Lysergic Acid: The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.
Mescaline: Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
Nicotine: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Vitamin B 6: VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.
