2026 ICD-10-CM Diagnosis Code D73.81Neutropenic splenomegaly

ICD-10-CM Codes›D50–D89›D70-D77›D73

ICD-10-CM D73.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D73.81 is a billable ICD-10-CM diagnosis code for neutropenic splenomegaly. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as Doan-Wiseman syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

Code Identity

ICD-10-CM Code
D73.81
Billable Status
Yes — Valid for Submission
Code Describes
Neutropenic splenomegaly
Short Description
Neutropenic splenomegaly
Same as the full description in the CMS dataset.
Parent Code
D73.8
Other diseases of spleen

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD73Diseases of spleen
This CodeD73.81Neutropenic splenomegaly

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Doan-Wiseman syndrome
  • Primary splenic neutropenia

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Werner-Schultz disease

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • Werner-Schultz (neutropenic splenomegaly)
    • Splenomegaly, splenomegalia(Bengal) (cryptogenic) (idiopathic) (tropical)
      • neutropenic
    • Syndrome
      • splenic
        • neutropenia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Spleen Diseases

Your spleen is an organ above your stomach and under your ribs on your left side. It is about as big as your fist. The spleen is part of your lymphatic system, which fights infection and keeps your body fluids in balance. It contains white blood cells that fight germs.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D73.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
289.53 Neutropenic splenomegaly
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D73.81Overview

Is D73.81 (Other diseases of spleen) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neutropenic splenomegaly on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D73.81 group to?

When neutropenic splenomegaly is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D73.81?

Under the General Equivalence Mappings, neutropenic splenomegaly converts to ICD-9-CM 289.53 (neutropenic splenomegaly). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.