2026 ICD-10-CM Diagnosis Code B56.1Rhodesiense trypanosomiasis

ICD-10-CM CodesA00–B99B50-B64B56

ICD-10-CM B56.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B56.1 is a billable ICD-10-CM diagnosis code for rhodesiense trypanosomiasis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 867 through 869. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 69 closely related codes. Coders also document this condition as african trypanosomiasis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
B56.1
Billable Status
Yes — Valid for Submission
Code Describes
Rhodesiense trypanosomiasis
Short Description
Rhodesiense trypanosomiasis
Same as the full description in the CMS dataset.
Parent Code
African trypanosomiasis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB50-B64Protozoal diseases
CategoryB56African trypanosomiasis
This CodeB56.1Rhodesiense trypanosomiasis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • African trypanosomiasis
  • Encephalitis caused by Trypanosoma brucei
  • Encephalitis caused by Trypanosoma brucei rhodesiense
  • Infection by Trypanosoma rhodesiense
  • Meningitis caused by Trypanosoma brucei
  • Trypanosoma brucei rhodesiense meningitis
  • Trypanosomiasis with encephalitis
  • Trypanosomiasis with meningitis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • East African sleeping sickness
  • Infection due to Trypanosoma brucei rhodesiense

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Parasitic Diseases

Parasites are living things that use other living things - like your body - for food and a place to live. You can get them from contaminated food or water, a bug bite, or sexual contact. Some parasitic diseases are easily treated and some are not.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B56.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
086.4 Rhodesian trypanosomias
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B56.1Overview

What is the ICD-10 code for rhodesiense trypanosomiasis?

The ICD-10-CM code for rhodesiense trypanosomiasis is B56.1 (sometimes written as B561). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is B56.1 (African trypanosomiasis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report rhodesiense trypanosomiasis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B56.1 group to?

When rhodesiense trypanosomiasis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 868, 869, with relative weights from 0.7297 to 2.0932 depending on complications. Higher weights mean higher Medicare reimbursement.

Is B56.1 a CC or MCC?

CMS lists B56.1 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 69 closely related codes in its exclusion list.

What is the ICD-9 equivalent of B56.1?

Under the General Equivalence Mappings, rhodesiense trypanosomiasis converts to ICD-9-CM 086.4 (rhodesian trypanosomias). The mapping is a direct match.