2027 ICD-10-CM Diagnosis Code B33.4Hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS]
ICD-10-CM Codes›A00–B99›B25-B34›B33
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Not Chronic
B33.4 is a billable ICD-10-CM diagnosis code for hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS]. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 865 through 866. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 25 closely related codes. Coders also document this condition as disease caused by Hantavirus. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Viral infection.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Disease caused by Hantavirus
- Hantavirus pulmonary syndrome
- Sin Nombre virus encephalitis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to B33.4: its own notes plus those printed at Chapter 1. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- diseases generally recognized as communicable or transmissible
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Hantavirus disease with pulmonary manifestations
- Sin nombre virus disease
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify any associated acute kidney failure (N17.9)
- code to identify resistance to antimicrobial drugs (Z16.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name B33.4, its category, or a range that includes it.
Applicable To 1
These notes mention B33.4.
- O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
Syndrome See Also: Disease;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Hantavirus Infections
Hantavirus pulmonary syndrome (HPS) is a rare viral infection caused by several strains of the hantavirus. It is spread by mice and rats. They shed the virus in their urine, droppings, and saliva. Tiny droplets with the virus can enter the air.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert B33.4 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About B33.4Overview
What is the ICD-10 code for hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS]?
The ICD-10-CM code for hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS] is B33.4 (sometimes written as B334). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is B33.4 (Other viral diseases, not elsewhere classified) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS] on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does B33.4 group to?
When hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS] is the principal diagnosis on an inpatient stay, it groups to MS-DRG 866, 865, with relative weights from 0.8691 to 1.3153 depending on complications. Higher weights mean higher Medicare reimbursement.
Is B33.4 a CC or MCC?
CMS lists B33.4 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 25 closely related codes in its exclusion list.
Can B33.4 be reported with A98.5?
Not as a rule. The Excludes1 note on B33.4 lists "hantavirus disease with renal manifestations (A98.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
