2026 ICD-10-CM Diagnosis Code B00.81Herpesviral hepatitis

ICD-10-CM Codes›A00–B99›B00-B09›B00

ICD-10-CM B00.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B00.81 is a billable ICD-10-CM diagnosis code for herpesviral hepatitis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 393 through 395, 974 through 976. Coders also document this condition as Epstein-Barr virus hepatitis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hepatitis and Viral infection.

Code Identity

ICD-10-CM Code
B00.81
Billable Status
Yes — Valid for Submission
Code Describes
Herpesviral hepatitis
Short Description
Herpesviral hepatitis
Same as the full description in the CMS dataset.
Parent Code
B00.8
Other forms of herpesviral infections

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB00-B09Viral infections characterized by skin and mucous membrane lesions
CategoryB00Herpesviral [herpes simplex] infections
This CodeB00.81Herpesviral hepatitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Epstein-Barr virus hepatitis
  • Hepatitis caused by human herpes simplex virus

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Hepatitis
      • herpesviral
    • Herpes, herpesvirus, herpetic
      • simplex
        • hepatitis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF007
Hepatitis
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INF008
Viral infection
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Herpes Simplex

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted infection (STI). It affects the genitals, buttocks or anal area.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B00.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
054.71 Visceral herpes simplex
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B00.81Overview

Is B00.81 (Other forms of herpesviral infections) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report herpesviral hepatitis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B00.81 group to?

When herpesviral hepatitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 393, 394, 395, 974, 975, 976, with relative weights from 0.6490 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of B00.81?

Under the General Equivalence Mappings, herpesviral hepatitis converts to ICD-9-CM 054.71 (visceral herpes simplex). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.