Version 2024

No Valid Principal Dx

Convert to ICD-9

2024 ICD-10-CM Diagnosis Code R74.8

Abnormal levels of other serum enzymes

ICD-10-CM Code:: R74.8
ICD-10 Code for:: Abnormal levels of other serum enzymes
Is Billable?: Yes - Valid for Submission
Chronic Condition Indicator: ^[1]: Not chronic
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Table of Contents

Code Information
Approximate Synonyms
Clinical Classification
Tabular List of Diseases and Injuries
Index to Diseases and Injuries References
Diagnostic Related Groups Mapping
Convert to ICD-9 Code
Patient Education
Other Codes Used Similar Conditions
Code History

Code Classification

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
(R00–R99)
- Abnormal findings on examination of blood, without diagnosis
  (R70-R79)
  - Abnormal serum enzyme levels
    (R74)

R74.8 is a billable diagnosis code used to specify a medical diagnosis of abnormal levels of other serum enzymes. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Absence of renin secretion
Absent renal function
Alkaline phosphatase above reference range
Alkaline phosphatase bone isoenzyme above reference range
Alkaline phosphatase bone isoenzyme below reference range
Creatine kinase below reference range
Creatine kinase below reference range
Creatine kinase level above reference range
Deficiency of alkaline phosphatase
Finding of gamma-glutamyl transferase level
Finding of gamma-glutamyl transferase level
Finding of gamma-glutamyl transferase level
Finding of plasma creatine kinase level
Finding of plasma creatine kinase level
Finding of serum creatine kinase level
Finding of serum creatine kinase level
Finding of serum creatine kinase level
Gamma-enolase level above reference range
Gamma-glutamyl transferase above reference range
Gamma-glutamyl transferase below reference range
Gamma-glutamyl transferase level outside reference range
High lipase level in serum
Intestinal alkaline phosphatase above reference range
Intestinal alkaline phosphatase below reference range
Isolated asymptomatic elevation of creatine phosphokinase
Liver enzymes level above reference range
Liver enzymes level above reference range due to cystic fibrosis
Low alkaline phosphatase due to chronic kidney disease
Pancreatic enzyme level above reference range
Placental alkaline phosphatase above reference range
Placental alkaline phosphatase below reference range
Plasma creatine kinase above reference range
Plasma creatine kinase below reference range
Serum 5-nucleotidase level above reference range
Serum acid phosphatase above reference range
Serum acid phosphatase below reference range
Serum alkaline phosphatase above reference range
Serum alkaline phosphatase below reference range
Serum alkaline phosphatase level - finding
Serum alkaline phosphatase level - finding
Serum amylase above reference range
Serum amylase outside reference range
Serum amylase above reference range
Serum creatine kinase above reference range
Serum creatine kinase below reference range
Serum lactate dehydrogenase level above reference range

Clinical Classification

Clinical Category is Abnormal findings without diagnosis
CCSR Category Code: SYM017
Inpatient Default CCSR: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default CCSR: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Abnormal level of acid phosphatase
Abnormal level of alkaline phosphatase
Abnormal level of amylase
Abnormal level of lipase triacylglycerol lipase

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

- Abnormal, abnormality, abnormalities - See Also: Anomaly;
- - serum level (of)
  - - acid phosphatase - R74.8
  - - alkaline phosphatase - R74.8
  - - amylase - R74.8
  - - enzymes - R74.9
    - - specified NEC - R74.8
  - - lipase - R74.8
  - - triacylglycerol lipase - R74.8

- Elevated, elevation
- - liver function
  - - test - R79.89
    - - alkaline phosphatase - R74.8
    - - hepatic enzyme - R74.8

R74.8 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

MS-DRG	MS-DRG Title	MCD	Relative Weight
947	SIGNS AND SYMPTOMS WITH MCC	23	1.2516
948	SIGNS AND SYMPTOMS WITHOUT MCC	23	0.801

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Convert R74.8 to ICD-9-CM

ICD-9-CM Code: 790.5 - Abn serum enzy level NEC
Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Code History

FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.