ICD-10-CM Use Additional Code Notes · Chapter 2 · FY 2027 C00-D49

Use Additional Code Notes in Chapter 2: Neoplasms ICD-10-CM

A Use Additional Code note means a second code should be added, after this one, to fully describe the condition. In Chapter 2 (C00-D49), notes printed in the chapter name other codes 135 times, and Use Additional Code Notes anywhere in the Tabular List name the chapter’s codes 3 times, covering 3 distinct codes, categories and ranges. Switch views to read the list either way.

✓ From the official FY 2027 ICD-10-CM Tabular ListDefinitions follow the Official Guidelines, Section I.A
135
References in Its Notes
3
References to Its Codes
3
Chapter Codes Named
C00-D49
Chapter 2
Chapter 2

Use Additional Code Notes by the code that carries the note

32 of 32 shown
  • C00 Malignant neoplasm of lip applies to 9 codes
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C01 Malignant neoplasm of base of tongue
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C02 Malignant neoplasm of other and unspecified parts of tongue applies to 7 codes
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C03 Malignant neoplasm of gum applies to 3 codes
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C04 Malignant neoplasm of floor of mouth applies to 4 codes
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C05 Malignant neoplasm of palate applies to 5 codes
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C06 Malignant neoplasm of other and unspecified parts of mouth applies to 6 codes
    • alcohol abuse and dependence (F10.-)
    • history of tobacco dependence (Z87.891)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C07 Malignant neoplasm of parotid gland
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C08 Malignant neoplasm of other and unspecified major salivary glands applies to 3 codes
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C09 Malignant neoplasm of tonsil applies to 4 codes
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C10 Malignant neoplasm of oropharynx applies to 7 codes
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C11 Malignant neoplasm of nasopharynx applies to 6 codes
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C12 Malignant neoplasm of pyriform sinus
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C13 Malignant neoplasm of hypopharynx applies to 5 codes
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx applies to 3 codes
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C15 Malignant neoplasm of esophagus applies to 5 codes
    • alcohol abuse and dependence (F10.-)
  • C16 Malignant neoplasm of stomach applies to 9 codes
    • alcohol abuse and dependence (F10.-)
  • C22 Malignant neoplasm of liver and intrahepatic bile ducts applies to 8 codes
  • C25 Malignant neoplasm of pancreas applies to 8 codes
    • alcohol abuse and dependence (F10.-)
  • C32 Malignant neoplasm of larynx applies to 6 codes
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C33 Malignant neoplasm of trachea
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C34 Malignant neoplasm of bronchus and lung applies to 16 codes
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs applies to 2 codes
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • C40 Malignant neoplasm of bone and articular cartilage of limbs applies to 18 codes
    • code to identify major osseous defect, if applicable (M89.7-)
  • C50 Malignant neoplasm of breast applies to 57 codes
    • code to identify estrogen, and other hormones and factors receptor status (Z17.-)
  • C61 Malignant neoplasm of prostate
    • hormone sensitivity status (Z19.1-Z19.2)
    • rising PSA following treatment for malignant neoplasm of prostate (R97.21)
  • C7A Malignant neuroendocrine tumors applies to 23 codes
  • C84.7A Anaplastic large cell lymphoma, ALK-negative, breast
    • breast implant status (Z98.82)
    • personal history of breast implant removal (Z98.86)
  • D00.0 Carcinoma in situ of lip, oral cavity and pharynx applies to 9 codes
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • D02 Carcinoma in situ of middle ear and respiratory system applies to 7 codes
    • exposure to environmental tobacco smoke (Z77.22)
    • exposure to tobacco smoke in the perinatal period (P96.81)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
  • D3A Benign neuroendocrine tumors applies to 22 codes
  • D46 Myelodysplastic syndromes applies to 11 codes
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Use Additional Code Notes anywhere in the Tabular List, including notes in other chapters.

Questions About Use Additional Code Notes

What does a Use Additional Code note mean?

A Use Additional Code note tells you to add a second code, reported after the code that carries the note, to describe the condition completely. In an etiology/manifestation pair it sits at the etiology code and points to the manifestation (Section I.A.13). The FY 2027 Tabular List has 1,491 of them; 1,174 name other codes, with 1,438 references to 389 distinct codes, categories and ranges.

Where does the additional code go?

After the code carrying the note. For etiology/manifestation pairs the Guidelines are explicit: the etiology is sequenced first, followed by the manifestation code.

Related References

Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.