2027 ICD-10-CM Diagnosis Code Z17Estrogen, and other hormones and factors receptor status

ICD-10-CM Codes›Z00–Z99›Z17›Z17

ICD-10-CM Z17
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Z17 is a non-billable ICD-10-CM category code for estrogen, and other hormones and factors receptor status, so it cannot be submitted on claims. Use a more specific code from this category instead, such as Z17.0, Z17.1, Z17.21, and Z17.22.

Code Identity

ICD-10-CM Code
Z17
Billable Status
No — Non-Billable Category
Code Describes
Estrogen, and other hormones and factors receptor status
Short Description
Estrogen, and other hormones and factors receptor status
Same as the full description in the CMS dataset.
Chapter
Z17
Estrogen, and other hormones and factors receptor status

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ17Estrogen, and other hormones and factors receptor status
CategoryZ17Estrogen, and other hormones and factors receptor status
This CodeZ17Estrogen, and other hormones and factors receptor status

Specific Coding for Estrogen, and other hormones and factors receptor statusOverview

Non-specific codes like Z17 require more characters. Use one of these billable codes instead:

  • Use Z17.0 for Estrogen receptor positive status [ER+]

  • Use Z17.1 for Estrogen receptor negative status [ER-]

  • Z17.2 for Progesterone receptor status

  • Use Z17.21 for Progesterone receptor positive status

  • Use Z17.22 for Progesterone receptor negative status

  • Z17.3 for Human epidermal growth factor 2 receptor

  • Use Z17.31 for Human epidermal growth factor receptor 2 positive status

  • Use Z17.32 for Human epidermal growth factor receptor 2 negative status

  • Z17.4 for Combined receptor status

  • Z17.41 for Hormone receptor positive

  • Z17.42 for Hormone receptor negative

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Z17: its own notes plus those printed at Chapter 21. A note printed at a category, block or chapter applies to every code under it.

Code First

The underlying condition named in the note is sequenced before this code.

  • malignant neoplasm, such as:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of ovary (C56.-)

Notes

General instructions on how these codes are used.

On Z17 itself
From Chapter 21 (Z00-Z99) Factors influencing health status and contact with health services applies to 1,425 codes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Z17, its category, or a range that includes it.

Use Additional Code 1

These codes say to use an additional code from the note, and Z17 is one of the codes named.

  • C50 Malignant neoplasm of breast
    code to identify estrogen, and other hormones and factors receptor status (Z17.-)

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Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Z17Overview

What is the ICD-10 code for estrogen, and other hormones and factors receptor status?

Z17 is the ICD-10-CM category for estrogen, and other hormones and factors receptor status, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is Z17 (Estrogen, and other hormones and factors receptor status) a billable code?

No. This is a category header that groups the codes for estrogen, and other hormones and factors receptor status, and headers cannot be submitted on claims. Claims for estrogen, and other hormones and factors receptor status need a more specific code from this category, such as Z17.0, Z17.1, and Z17.21.

What is coded first with Z17?

The Code First note reads: malignant neoplasm, such as: malignant neoplasm of breast (C50.-); malignant neoplasm of ovary (C56.-). When one of these applies, it is sequenced before Z17.