2026 ICD-10-CM Diagnosis Code Z95.3Presence of xenogenic heart valve

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z95

ICD-10-CM Z95.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z95.3 is a billable ICD-10-CM diagnosis code for presence of xenogenic heart valve. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 314 through 316. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Implant, device or graft related encounter; and Nonrheumatic and unspecified valve disorders.

Code Identity

ICD-10-CM Code
Z95.3
Billable Status
Yes — Valid for Submission
Code Describes
Presence of xenogenic heart valve
Short Description
Presence of xenogenic heart valve
Same as the full description in the CMS dataset.
Parent Code
Z95
Presence of cardiac and vascular implants and grafts

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ95Presence of cardiac and vascular implants and grafts
This CodeZ95.3Presence of xenogenic heart valve

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z95.3.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z95.3 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Biologic cardiac valve prosthesis in situ
  • History of aortic valve replacement
  • History of artificial heart valve
  • History of heart valve repair
  • History of mitral valve replacement
  • History of porcine aortic valve replacement
  • History of porcine cardiac valve replacement
  • History of porcine mitral valve replacement
  • History of repair of mitral valve
  • History of replacement of mitral valve with tissue graft
  • History of tissue graft aortic valve replacement
  • History of tissue graft heart valve replacement
  • Prosthetic heart valve in situ

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Presence(of)
      • heart valve implant (functional)
        • xenogenic
    • Presence(of)
      • implanted device (artificial) (functional) (prosthetic)
        • heart valve
          • xenogenic
    • Replacement by artificial or mechanical device or prosthesis of
      • heart
        • valve
          • xenogenic
    • Transplant(ed) (status)
      • heart
        • valve
          • xenogenic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC009
Implant, device or graft related encounter
Default principal diagnosis: inpatient No · outpatient No
CCSR CIR003
Nonrheumatic and unspecified valve disorders
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Heart Valve Diseases

Heart valve disease happens when one or more of your heart valves don't work well.

The full article covers:

  • What are heart valve diseases?
  • What are the types of heart valve diseases?
  • What causes heart valve diseases?
  • Who is more likely to develop heart valve diseases?
  • What are the symptoms of heart valve diseases?
  • What other problems can heart valve diseases cause?
  • How is heart valve disease diagnosed?
  • What are the treatments for heart valve diseases?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z95.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V42.2 Heart valve transplant
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z95.3Overview

Is Z95.3 (Presence of cardiac and vascular implants and grafts) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report presence of xenogenic heart valve on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does Z95.3 group to?

On inpatient claims, presence of xenogenic heart valve maps to MS-DRG 314, 315, 316, with relative weights from 0.6821 to 2.0852 depending on complications. Higher weights mean higher Medicare reimbursement.

Can Z95.3 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because presence of xenogenic heart valve describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z95.3 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for presence of xenogenic heart valve on inpatient claims.

What is the ICD-9 equivalent of Z95.3?

Under the General Equivalence Mappings, presence of xenogenic heart valve converts to ICD-9-CM V42.2 (heart valve transplant). The mapping is approximate, so confirm the match fits the documentation.