2027 ICD-10-CM Diagnosis Code Y64Contaminated medical or biological substances

ICD-10-CM Codes›V01–Y99›Y62-Y69›Y64

ICD-10-CM Y64
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Y64 is a non-billable ICD-10-CM category code for contaminated medical or biological substances, so it cannot be submitted on claims. Use a more specific code from this category instead, such as Y64.0, Y64.1, Y64.8, and Y64.9.

Code Identity

ICD-10-CM Code
Y64
Billable Status
No — Non-Billable Category
Code Describes
Contaminated medical or biological substances
Short Description
Contaminated medical or biological substances
Same as the full description in the CMS dataset.
Chapter
Y62-Y69
Misadventures to patients during surgical and medical care

Code Classification

ChapterV01–Y99External causes of morbidity and mortality
SectionY62-Y69Misadventures to patients during surgical and medical care
CategoryY64Contaminated medical or biological substances
This CodeY64Contaminated medical or biological substances

Specific Coding for Contaminated medical or biological substancesOverview

Non-specific codes like Y64 require more characters. Use one of these billable codes instead:

  • Use Y64.0 for Contaminated medical or biological substance, transfused or infused

  • Use Y64.1 for Contaminated medical or biological substance, injected or used for immunization

  • Use Y64.8 for Contaminated medical or biological substance administered by other means

  • Use Y64.9 for Contaminated medical or biological substance administered by unspecified means

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Y64: its own notes plus those printed at block Y62-Y84, block Y62-Y69, and Chapter 20. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block Y62-Y84 Complications of medical and surgical care applies to 115 codes
  • complications of medical devices
  • surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block Y62-Y69 Misadventures to patients during surgical and medical care applies to 33 codes
  • surgical and medical procedures as the cause of abnormal reaction of the patient, without mention of misadventure at the time of the procedure (Y83-Y84)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block Y62-Y69 Misadventures to patients during surgical and medical care applies to 33 codes
  • breakdown or malfunctioning of medical device (during procedure) (after implantation) (ongoing use) (Y70-Y82)

Notes

General instructions on how these codes are used.

From Chapter 20 (V00-Y99) External causes of morbidity and mortality applies to 7,461 codes
  • This chapter permits the classification of environmental events and circumstances as the cause of injury, and other adverse effects. Where a code from this section is applicable, it is intended that it shall be used secondary to a code from another chapter of the Classification indicating the nature of the condition. Most often, the condition will be classifiable to Chapter 19, Injury, poisoning and certain other consequences of external causes (S00-T88). Other conditions that may be stated to be due to external causes are classified in Chapters I to XVIII. For these conditions, codes from Chapter 20 should be used to provide additional information as to the cause of the condition.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Y64, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming Y64: they are not reported together with it, unless the two conditions are unrelated.

  • Block Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
    misadventures to patients during surgical and medical care, classifiable to (Y62-Y69) names Y62-Y69, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming Y64: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
    misadventure to patients during surgical and medical care, classifiable to (Y62-Y69) names Y62-Y69, which includes this code

Use Additional Code 1

These codes say to use an additional code from the note, and Y64 is one of the codes named.

  • Block T80-T88 Complications of surgical and medical care, not elsewhere classified
    code to identify devices involved and details of circumstances (Y62-Y82) names Y62-Y82, which includes this code

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Y64Overview

What is the ICD-10 code for contaminated medical or biological substances?

Y64 is the ICD-10-CM category for contaminated medical or biological substances, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is Y64 (Contaminated medical or biological substances) a billable code?

No. This is a category header that groups the codes for contaminated medical or biological substances, and headers cannot be submitted on claims. Claims for contaminated medical or biological substances need a more specific code from this category, such as Y64.0, Y64.1, and Y64.8.