2026 ICD-10-CM Diagnosis Code R89.1Abnormal level of hormones in specimens from other organs, systems and tissues

ICD-10-CM CodesR00–R99R83-R89R89

ICD-10-CM R89.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R89.1 is a billable ICD-10-CM diagnosis code for abnormal level of hormones in specimens from other organs, systems and tissues. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 947 through 948. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.

Code Identity

ICD-10-CM Code
R89.1
Billable Status
Yes — Valid for Submission
Code Describes
Abnormal level of hormones in specimens from other organs, systems and tissues
Short Description
Abnormal level of hormones in specimens from oth org/tiss
Parent Code
Abnormal findings in specimens from other organs, systems and tissues

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR83-R89Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
CategoryR89Abnormal findings in specimens from other organs, systems and tissues
This CodeR89.1Abnormal level of hormones in specimens from other organs, systems and tissues

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • 11-deoxy, 17-hydroxycorticosterone level above reference range
  • 11-deoxy, 17-hydroxycorticosterone level below reference range
  • 11-deoxycorticosterone level above reference range
  • 11-deoxycorticosterone level below reference range
  • 17-ketogenic steroids level above reference range
  • 17-ketogenic steroids level below reference range
  • 17-ketosteroids level above reference range
  • 17-ketosteroids level below reference range
  • 3,3'-diiodothyronine level above reference range
  • 3,3'-diiodothyronine level below reference range
  • Abnormal 11-deoxy, 17-hydroxycorticosterone
  • Abnormal 11-deoxycorticosterone
  • Abnormal 17-ketogenic steroids
  • Abnormal 17-ketosteroids
  • Abnormal 3,3' diiodothyronine
  • Abnormal adrenal cortical hormone
  • Abnormal adrenocorticotropic hormone
  • Abnormal anti-diuretic hormone
  • Abnormal corticotropin releasing factor
  • Abnormal cortisone
  • Abnormal epinephrine
  • Abnormal female sex hormone
  • Abnormal glucagon
  • Abnormal human chorionic gonadotropin
  • Abnormal human growth hormone
  • Abnormal melanocyte stimulating hormone
  • Abnormal norepinephrine
  • Abnormal oxytocin
  • Abnormal pituitary follicle stimulating hormone
  • Abnormal pituitary gonadotropin
  • Abnormal pituitary luteinizing hormone
  • Abnormal pregnanediol
  • Abnormal protein hormone
  • Abnormal secretin
  • Abnormal steroid hormone
  • Abnormal testosterone
  • Abnormal thyroid hormone
  • Abnormal thyroxine
  • Abnormal triiodothyronine
  • Abnormal vanillylmandelic acid
  • Adrenal cortical hormone level above reference range
  • Adrenal cortical hormone level below reference range
  • Adrenocorticotropic hormone level above reference range
  • Adrenocorticotropic hormone level below reference range
  • Androgen level above reference range
  • Androgen level below reference range
  • Angiotensin II level above reference range
  • Angiotensin II level below reference range
  • Anti-diuretic hormone level above reference range
  • Anti-diuretic hormone level below reference range
  • B-type natriuretic peptide above reference range
  • Congenital hypoplasia of adrenal gland
  • Corticosterone level above reference range
  • Corticosterone level below reference range
  • Corticotropin releasing factor level above reference range
  • Corticotropin releasing factor level below reference range
  • Cortisol level above reference range
  • Cortisol level below reference range
  • Cortisol level outside reference range
  • Cortisone level above reference range
  • Cortisone level below reference range
  • Decreased estrogen level
  • Epinephrine level above reference range
  • Epinephrine level below reference range
  • Estradiol and follicle stimulating hormone above reference range
  • Estradiol level above reference range
  • Estradiol level below reference range
  • Estriol level above reference range
  • Estriol level below reference range
  • Estrogen level above reference range
  • Estrone level above reference range
  • Estrone level below reference range
  • Familial adrenal hypoplasia with absent pituitary luteinizing hormone
  • Female sex hormone outside reference range
  • Fetoplacental hormone above reference range
  • Fetoplacental hormone below reference range
  • Fetoplacental hormone level - finding
  • Fetoplacental hormones outside reference range
  • Finding of estriol level
  • Follicle-stimulating hormone level outside reference range
  • Free androgenic index above reference range
  • Free androgenic index below reference range
  • Free androgenic index outside reference range
  • Gastrointestinal hormone level - finding
  • Glucagon level above reference range
  • Glucagon level below reference range
  • Gonadotrophin levels above reference range
  • Gonadotrophin levels below reference range
  • Hormone abnormality
  • Hormone absence
  • Hormone decrease
  • Hormone increase
  • Human chorionic gonadotropin level above reference range
  • Human chorionic gonadotropin level below reference range
  • Human growth hormone level above reference range
  • Human growth hormone level below reference range
  • Human placental lactogen outside reference range
  • Hyperproinsulinemia
  • Hypotestosteronism
  • Insulin level above reference range
  • Insulin level below reference range
  • Luteinizing hormone level outside reference range
  • Male sex hormones above reference range
  • Male sex hormones below reference range
  • Measurement procedure result absent
  • Melanocyte stimulating hormone level above reference range
  • Melanocyte stimulating hormone level below reference range
  • Norepinephrine level above reference range
  • Norepinephrine level below reference range
  • Oxytocin level above reference range
  • Oxytocin level below reference range
  • Pituitary follicle stimulating hormone below reference range
  • Pituitary follicle stimulating hormone level above reference range
  • Pituitary gonadotropin level above reference range
  • Pituitary gonadotropin level below reference range
  • Pituitary luteinizing hormone level above reference range
  • Pituitary luteinizing hormone level below reference range
  • Pituitary/adrenal hormone levels - finding
  • Pregnanediol level above reference range
  • Pregnanediol level below reference range
  • Pregnanetriol above reference range
  • Pregnanetriol level below reference range
  • Progesterone level above reference range
  • Progesterone level below reference range
  • Prolactin level above reference range
  • Prolactin level below reference range
  • Protein-bound iodine above reference range
  • Secretin level above reference range
  • Secretin level below reference range
  • Serotonin level above reference range
  • Serotonin level below reference range
  • Serum androstenedione above reference range
  • Serum androstenedione below reference range
  • Serum androstenedione outside reference range
  • Serum estradiol levels below reference range
  • Serum human chorionic gonadotropin level, beta subunit above reference range
  • Serum progesterone above reference range
  • Serum progesterone below reference range
  • Serum progesterone level outside reference range
  • Serum T3 level above reference range
  • Serum T3 level below reference range
  • Serum testosterone above reference range
  • Serum testosterone below reference range
  • Serum testosterone level outside reference range
  • Serum thyroid stimulating hormone level outside reference range
  • Serum thyroxine level outside reference range
  • T3 uptake above reference range
  • T3 uptake below reference range
  • Testosterone level above reference range
  • Testosterone level below reference range
  • Thyroid hormone level above reference range
  • Thyroid hormone level below reference range
  • Thyroxine level above reference range
  • Thyroxine level below reference range
  • Triiodothyronine level above reference range
  • Triiodothyronine level below reference range
  • Triiodothyronine uptake test outside reference range

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abnormal, abnormality, abnormalities
      • specimen
        • specified organ, system and tissue NOS
          • hormones

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM017
Abnormal findings without diagnosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Convert R89.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
792.9 Abn find-body subst NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R89.1Overview

Is R89.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report abnormal level of hormones in specimens from other organs, systems and tissues on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R89.1 group to?

When abnormal level of hormones in specimens from other organs, systems and tissues is the principal diagnosis on an inpatient stay, it groups to MS-DRG 947, 948, with relative weights from 0.8005 to 1.2694 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R89.1 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the abnormal level of hormones in specimens from other organs, systems and tissues is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R89.1?

Under the General Equivalence Mappings, abnormal level of hormones in specimens from other organs, systems and tissues converts to ICD-9-CM 792.9 (abn find-body subst NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.