2026 ICD-10-CM Diagnosis Code R78.89Finding of other specified substances, not normally found in blood
ICD-10-CM Codes›R00–R99›R70-R79›R78
- Billable — Valid for Submission
- Not Chronic
R78.89 is a billable ICD-10-CM diagnosis code for finding of other specified substances, not normally found in blood. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 947 through 948. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal lithium level in blood
- Finding of serum phenylalanine level
- Infectious agent in bloodstream
- Lithium level - finding
- Lithium: blood level - finding
- Opiate agonist detected in blood specimen
- Phenobarbitone level - finding
- Phenylalanine level - finding
- Phenytoin level - finding
- Serum amino acid levels - finding
- Valproate level - finding
- Valproate level below reference range
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Finding of abnormal level of lithium in blood
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Abnormal, abnormality, abnormalities See Also: Anomaly;
lithium R78.89
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Convert R78.89 to ICD-9-CMHistory
Code HistoryHistory
Questions About R78.89Overview
What is the ICD-10 code for finding of other specified substances, not normally found in blood?
The ICD-10-CM code for finding of other specified substances, not normally found in blood is R78.89 (sometimes written as R7889). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is R78.89 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report finding of other specified substances, not normally found in blood on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does R78.89 group to?
When finding of other specified substances, not normally found in blood is the principal diagnosis on an inpatient stay, it groups to MS-DRG 947, 948, with relative weights from 0.8005 to 1.2694 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R78.89 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the finding of other specified substances, not normally found in blood is established, that condition takes the principal position instead.
What is the ICD-9 equivalent of R78.89?
Under the General Equivalence Mappings, finding of other specified substances, not normally found in blood converts to ICD-9-CM 790.6 (abn blood chemistry NEC) and 790.99 (oth nspcf finding blood). The mapping is approximate, so confirm the match fits the documentation.
