2026 ICD-10-CM Diagnosis Code R78.2Finding of cocaine in blood

ICD-10-CM Codes›R00–R99›R70-R79›R78

ICD-10-CM R78.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R78.2 is a billable ICD-10-CM diagnosis code for finding of cocaine in blood. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 947 through 948. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings related to substance use.

Code Identity

ICD-10-CM Code
R78.2
Billable Status
Yes — Valid for Submission
Code Describes
Finding of cocaine in blood
Short Description
Finding of cocaine in blood
Same as the full description in the CMS dataset.
Parent Code
R78
Findings of drugs and other substances, not normally found in blood

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR70-R79Abnormal findings on examination of blood, without diagnosis
CategoryR78Findings of drugs and other substances, not normally found in blood
This CodeR78.2Finding of cocaine in blood

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Finding of cocaine in blood

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Findings, abnormal, inconclusive, without diagnosis
      • in blood (of substance not normally found in blood)
        • cocaine

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM009
Abnormal findings related to substance use
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Cocaine

Cocaine is a very addictive drug that is made from leaves of the coca plant found in South America. It is mostly available as an illegal drug that some people use to get high. In rare cases, it is also used as a prescription drug for for anesthesia during certain surgeries.

The full article covers:

  • What is cocaine?
  • How do people use cocaine?
  • What are the short-term effects of cocaine?
  • What are the long-term effects of cocaine?
  • Can a person overdose on cocaine?
  • What are the treatments for cocaine use disorder?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R78.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
790.99 Oth nspcf finding blood
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R78.2Overview

Is R78.2 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report finding of cocaine in blood on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R78.2 group to?

When finding of cocaine in blood is the principal diagnosis on an inpatient stay, it groups to MS-DRG 947, 948, with relative weights from 0.8005 to 1.2694 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R78.2 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the finding of cocaine in blood is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R78.2?

Under the General Equivalence Mappings, finding of cocaine in blood converts to ICD-9-CM 790.99 (oth nspcf finding blood). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.