R65 - Symptoms and signs specifically associated with systemic inflammation and infection

Version 2023
No Valid Principal Dx
ICD-10:R65
Short Description:Symp and signs specifically assoc w sys inflam and infct
Long Description:Symptoms and signs specifically associated with systemic inflammation and infection
Status: Not Valid for Submission
Version:ICD-10-CM 2023
Code Classification:
  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)
    • General symptoms and signs (R50-R69)
      • Symp and signs specifically assoc w sys inflam and infct (R65)

R65 is a non-specific and non-billable ICD-10 code code, consider using a code with a higher level of specificity for a diagnosis of symptoms and signs specifically associated with systemic inflammation and infection. The code is not specific and is NOT valid for the year 2023 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Specific Coding for Symp and signs specifically assoc w sys inflam and infct

Non-specific codes like R65 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for symp and signs specifically assoc w sys inflam and infct:

  • NON-BILLABLE CODE - R65.1 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin
  • BILLABLE CODE - Use R65.10 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
  • BILLABLE CODE - Use R65.11 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
  • NON-BILLABLE CODE - R65.2 for Severe sepsis
  • BILLABLE CODE - Use R65.20 for Severe sepsis without septic shock
  • BILLABLE CODE - Use R65.21 for Severe sepsis with septic shock

Code History