ICD-10-CM Code R65.1

Systemic inflammatory response syndrome (SIRS) of non-infectious origin

Version 2020 Non-Billable Code No Valid Principal Dx

Not Valid for Submission

R65.1 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of systemic inflammatory response syndrome (sirs) of non-infectious origin. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10:R65.1
Short Description:SIRS of non-infectious origin
Long Description:Systemic inflammatory response syndrome (SIRS) of non-infectious origin

Consider the following ICD-10 codes with a higher level of specificity:

  • R65.10 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
  • R65.11 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code R65.1:

Code First

Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
  • underlying condition, such as:
  • heatstroke T67.0
  • injury and trauma S00 T88

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • sepsis- code to infection
  • severe sepsis R65.2

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)
    • General symptoms and signs (R50-R69)
      • Symp and signs specifically assoc w sys inflam and infct (R65)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020